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Radiopharmaceuticals for Tumor-Targeted Imaging: Overview

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Targeted Molecular Imaging in Oncology

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Abstract

Improvement of scintigraphic tumor diagnosis, prognosis, planning, and monitoring of cancer treatment is clearly determined by development of more tumor-specific radiopharmaceuticals. Application of molecular targets for cancer imaging, therapy, and prevention are the major focus of research projects. Radionuclide imaging modalities (positron emission tomography, PET; single photon emission computed tomography, SPECT) are diagnostic cross-sectional imaging techniques that map the location and concentration of radionuclidelabeled radiotracers. Although computed tomography (CT) and magnetic resonance imaging (MRI) provide considerable anatomical information about the location and the extent of tumors, these imaging modalities cannot adequately differentiate invasive lesions from edema, radiation necrosis, or gliosis.

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Authors
  1. David J. Yang
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  2. Tomio Inoue
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  3. E. Edmund Kim
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Editors and Affiliations

  1. Departments of Nuclear Medicine and Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 77030, Houston, TX, USA

    E. Edmund Kim MD  & David J. Yang PhD  & 

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Yang, D.J., Inoue, T., Kim, E.E. (2001). Radiopharmaceuticals for Tumor-Targeted Imaging: Overview. In: Kim, E.E., Yang, D.J. (eds) Targeted Molecular Imaging in Oncology. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3505-5_5

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