Imaging of Signal Transduction and Antisense Imaging

  • David J. Yang
  • E. Edmund Kim


An estimated 600,000 human deaths result from cancer, and 1.5 million new cases of cancer are diagnosed each year. Approximately 5% of cancers are hereditary. The survival rate of patients diagnosed with early-stage cancer is higher than those with advanced-stage disease [1–3]. The diagnosis of cancer is made by pathological evaluation of tissue. Due to rapid developments in molecular biology, more and more biomarkers and gene markers are being developed for early detection of tumors. Trends in molecular biology research have focused from drug administration followed by angiogenesis to drugs in the micromolecular pathway. Molecular pathways that mediate signal transduction, cell-cycle traversal, apoptosis, hypoxia, and necrosis provide better understanding of molecular-targeted therapy.


Breast Cancer Endometrial Cancer Tamoxifen Therapy Dictyostelium Discoideum Folate Receptor 
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© Springer Science+Business Media New York 2001

Authors and Affiliations

  • David J. Yang
  • E. Edmund Kim

There are no affiliations available

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