Abstract
Dynamic magnetic resonance imaging (MRI) with rapid sequential image acquisition after bolus injection of gadolinium-diethylene triaminepentaacetic acid (Gd-DTPA) can be used to differentiate benign from malignant lesions. Approximately 84% of malignant tumors exhibited slope values (the slope of the contrastenhancement-over-time curve) higher than 30% per minute; 72% of benign tumors showed slopes lower than 30% per minute [1]. Both benign and malignant tumors showed some overlap resulting in an accuracy of approximately 80 %. The slope values of the time intensity curve of postcontrast dynamic sequences and peak enhancement rates were calculated during the first minute after contrast administration on a pixel-by-pixel basis using a linear fitting algorithm.
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Kim, E.E. (2001). Magnetic Resonance Characteristics of Tumors. In: Kim, E.E., Yang, D.J. (eds) Targeted Molecular Imaging in Oncology. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3505-5_13
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DOI: https://doi.org/10.1007/978-1-4757-3505-5_13
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