Pancreatic Tumors: Pathophysiology and Treatment

  • Keith D. Lillemoe


The entire spectrum of benign and malignant pancreatic neoplasms can be seen in the elderly. Adenocarcinoma of the pancreas is by far the most important of these conditions, reflecting the frequency and lethality of the disease and the complexity of treatment. The incidence of pancreatic cancer rose dramatically from the 1930s until the mid-1970s, nearly doubling during this time period. Since 1973, the incidence in the United States has remained stable at 8–9 per 100,000 population, with over 28,000 new cases diagnosed yearly1 Carcinoma of the pancreas is an extremely lethal disease with an overall estimated cure rate of less than 5%. Although it represents only 2–3% of all cancers, it results in more than 6% of cancer deaths. As the population ages, it can be expected that increasing numbers of elderly patients will be diagnosed and require treatment for pancreatic cancer.


Pancreatic Cancer Common Bile Duct Pancreatic Carcinoma Obstructive Jaundice Gastric Outlet Obstruction 
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© Springer Science+Business Media New York 2001

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  • Keith D. Lillemoe

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