Physiologic Changes in Cardiac Function with Aging

  • Wilbert S. Aronow
  • William H. Frishman


Age-related changes in the cardiovascular system, overt and occult cardiovascular disease, and decreased physical activity affect cardiovascular function in older persons. With aging, there is a loss of myocytes in both the left and right ventricles with a progressive increase in myocyte cell volume per nucleus in both ventricles.1 There is also a progressive decrease in the number of pacemaker cells in the sinus node, with only 10% of the number of cells present at age 20 remaining at age 75.2


Pulse Wave Velocity Diastolic Filling Isosorbide Dinitrate Valvular Aortic Stenosis Early Diastolic Filling 
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© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Wilbert S. Aronow
  • William H. Frishman

There are no affiliations available

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