Diagnosis and Management of Intrahepatic and Extrahepatic Cholangiocarcinoma
Abstract
Cholangiocarcinomas are malignant tumors that arise from the epithelium of the intrahepatic or extrahepatic bile ducts. Cholangiocarcinomas are rare compared with hepatocellular carcinoma, comprising less than 10% of primary malignancies of the liver (1). In the United States, approximately 3,000 patients are diagnosed with cholangiocarcinoma annually (2). The autopsy incidence of cholangiocarcinoma is low also, being reported in 0.089–0.46% of necropsies (1). Cholangiocarcinomas are diagnosed most frequently in the fifth and sixth decades of life (3). There is only a slight male preponderance of cases of cholangiocarcinoma. Cholangiocarcinomas can arise at any site in the intra- or extrahepatic biliary system, but perihilar tumors comprise two-thirds of the cases of cholangiocarcinoma (3) (Fig. 1).
Keywords
Bile Duct Primary Sclerosing Cholangitis Hepatic Duct Choledochal Cyst Extrahepatic Bile DuctPreview
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References
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