Skip to main content

Transduction

  • Chapter
  • 302 Accesses

Abstract

Transduction is the term used to designate bacteriophage-mediated transfer of DNA from one cell (a donor) to another cell (a recipient). It was first described by Zinder and Lederberg for Salmonella and phage P22, but has since been shown to occur in many other bacteria and to involve a variety of bacteriophages. Depending on which virus is involved, the donor cell DNA may or may not be associated with viral DNA inside the capsid of the bacteriophage. However, in all cases of transduction it is necessary for donor cells to lyse and for virions carrying host DNA (the transducing particles) to be capable of infecting new host cells. A cell that has acquired a recombinant phenotype by this process is called a transductant.

Keywords

  • Bacterial Genome
  • Generalize Transduction
  • Temperate Phage
  • Helper Phage
  • Transduce Phage

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

This is a preview of subscription content, access via your institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • DOI: 10.1007/978-1-4757-3258-0_9
  • Chapter length: 21 pages
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
eBook
USD   74.99
Price excludes VAT (USA)
  • ISBN: 978-1-4757-3258-0
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

General

  • Campbell, A. (1977). Defective bacteriophages and incomplete prophages, pp. 259–328. In: Fraenkel-Conrat, H., Wagner, R.R. (eds.), Comprehensive Virology, vol. 8. New York: Plenum Press.

    Google Scholar 

  • Nordeen, R.O., Currier, T.C. (1983). Generalized transduction in the phytopathogen Pseudomonas syringae. Applied and Environmental Microbiology 45: 1884–1889.

    PubMed  CAS  Google Scholar 

  • Susskind, M.M., Botstein, D. (1978). Molecular genetics of bacteriophage P22. Microbiological Reviews 42: 3 85–413.

    Google Scholar 

Specialized

  • Adams, M.B., Hayden, M., Casjens, S. (1983). On the sequential packaging of bacteriophage P22 DNA. Journal of Virology 46: 673–677.

    PubMed  CAS  Google Scholar 

  • Backhaus, H. (1985). DNA packaging initiation of Salmonella bacteriophage P22: Determination of cut sites within the DNA sequence coding for gene 3. Journal of Virology 55: 458–465.

    PubMed  CAS  Google Scholar 

  • Benson, N.R., Roth, J. (1997). A Salmonella phage-P22 mutant defective in abortive transduction. Genetics145: 17–27.

    PubMed  CAS  Google Scholar 

  • Blahova, J., Kralikova, K., Krcmery, V., Mikovicova, A., Bartonikova, N. (1998). Two high-frequency-transduction phage isolates from lysogenic strains of Pseudomonas aeruginosa transducing antibiotic resistance. Acta Virologica 42: 175–179.

    PubMed  CAS  Google Scholar 

  • Dhillon, T.S., Poon, A.P.W., Chan, D., Clark, A.J. (1998). General transducing phages like Salmonella phage P22 isolated using smooth strain of Escherichia coli as host. FEMS Microbiology Letters 161: 129–133.

    PubMed  CrossRef  CAS  Google Scholar 

  • Iida, S., Hiestand-Nauer, R., Sandmeier, H., Lehnherr, H., Arber, W. (1998). Accessory genes in the darA operon of bacteriophage P1 affect antirestriction function, generalized transduction, head morphogenesis, and host cell lysis. Virology 251: 49–58.

    PubMed  CrossRef  CAS  Google Scholar 

  • Sternberg, N. (1987). The production of generalized transducing phage by bacteriophage lambda. Gene 50: 69–85.

    CrossRef  Google Scholar 

  • Teifel-Greding, J. (1984). Transduction of multicopy plasmid pBR322 by bacteriophage Mu. Molecular and General Genetics 197: 169–174.

    PubMed  CrossRef  CAS  Google Scholar 

  • Yamamoto, N., Droffner, M.L., Yamamoto, S., Gemski, P., Baron, L.S. (1985). High-frequency transduction by phage hybrids between coliphage ϕ80 and Salmonella phage P22. Journal of General Virology 66: 1661–1667.

    PubMed  CrossRef  CAS  Google Scholar 

  • Young, K. K.Y , Edlin, G. (1983). Physical and genetical analysis of bacteriophage T4 generalized transduction. Molecular and General Genetics192: 241–246.

    PubMed  CrossRef  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

Copyright information

© 2000 Springer Science+Business Media New York

About this chapter

Cite this chapter

Birge, E.A. (2000). Transduction. In: Bacterial and Bacteriophage Genetics. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3258-0_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-3258-0_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-3260-3

  • Online ISBN: 978-1-4757-3258-0

  • eBook Packages: Springer Book Archive