Transduction

  • Edward A. Birge

Abstract

Transduction is the term used to designate bacteriophage-mediated transfer of DNA from one cell (a donor) to another cell (a recipient). It was first described by Zinder and Lederberg for Salmonella and phage P22, but has since been shown to occur in many other bacteria and to involve a variety of bacteriophages. Depending on which virus is involved, the donor cell DNA may or may not be associated with viral DNA inside the capsid of the bacteriophage. However, in all cases of transduction it is necessary for donor cells to lyse and for virions carrying host DNA (the transducing particles) to be capable of infecting new host cells. A cell that has acquired a recombinant phenotype by this process is called a transductant.

Keywords

Bacterial Genome Generalize Transduction Temperate Phage Helper Phage Transduce Phage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

General

  1. Campbell, A. (1977). Defective bacteriophages and incomplete prophages, pp. 259–328. In: Fraenkel-Conrat, H., Wagner, R.R. (eds.), Comprehensive Virology, vol. 8. New York: Plenum Press.Google Scholar
  2. Nordeen, R.O., Currier, T.C. (1983). Generalized transduction in the phytopathogen Pseudomonas syringae. Applied and Environmental Microbiology 45: 1884–1889.PubMedGoogle Scholar
  3. Susskind, M.M., Botstein, D. (1978). Molecular genetics of bacteriophage P22. Microbiological Reviews 42: 3 85–413.Google Scholar

Specialized

  1. Adams, M.B., Hayden, M., Casjens, S. (1983). On the sequential packaging of bacteriophage P22 DNA. Journal of Virology 46: 673–677.PubMedGoogle Scholar
  2. Backhaus, H. (1985). DNA packaging initiation of Salmonella bacteriophage P22: Determination of cut sites within the DNA sequence coding for gene 3. Journal of Virology 55: 458–465.PubMedGoogle Scholar
  3. Benson, N.R., Roth, J. (1997). A Salmonella phage-P22 mutant defective in abortive transduction. Genetics145: 17–27.PubMedGoogle Scholar
  4. Blahova, J., Kralikova, K., Krcmery, V., Mikovicova, A., Bartonikova, N. (1998). Two high-frequency-transduction phage isolates from lysogenic strains of Pseudomonas aeruginosa transducing antibiotic resistance. Acta Virologica 42: 175–179.PubMedGoogle Scholar
  5. Dhillon, T.S., Poon, A.P.W., Chan, D., Clark, A.J. (1998). General transducing phages like Salmonella phage P22 isolated using smooth strain of Escherichia coli as host. FEMS Microbiology Letters 161: 129–133.PubMedCrossRefGoogle Scholar
  6. Iida, S., Hiestand-Nauer, R., Sandmeier, H., Lehnherr, H., Arber, W. (1998). Accessory genes in the darA operon of bacteriophage P1 affect antirestriction function, generalized transduction, head morphogenesis, and host cell lysis. Virology 251: 49–58.PubMedCrossRefGoogle Scholar
  7. Sternberg, N. (1987). The production of generalized transducing phage by bacteriophage lambda. Gene 50: 69–85.CrossRefGoogle Scholar
  8. Teifel-Greding, J. (1984). Transduction of multicopy plasmid pBR322 by bacteriophage Mu. Molecular and General Genetics 197: 169–174.PubMedCrossRefGoogle Scholar
  9. Yamamoto, N., Droffner, M.L., Yamamoto, S., Gemski, P., Baron, L.S. (1985). High-frequency transduction by phage hybrids between coliphage ϕ80 and Salmonella phage P22. Journal of General Virology 66: 1661–1667.PubMedCrossRefGoogle Scholar
  10. Young, K. K.Y , Edlin, G. (1983). Physical and genetical analysis of bacteriophage T4 generalized transduction. Molecular and General Genetics192: 241–246.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Edward A. Birge
    • 1
  1. 1.Department of MicrobiologyArizona State UniversityTempeUSA

Personalised recommendations