Transduction is the term used to designate bacteriophage-mediated transfer of DNA from one cell (a donor) to another cell (a recipient). It was first described by Zinder and Lederberg for Salmonella and phage P22, but has since been shown to occur in many other bacteria and to involve a variety of bacteriophages. Depending on which virus is involved, the donor cell DNA may or may not be associated with viral DNA inside the capsid of the bacteriophage. However, in all cases of transduction it is necessary for donor cells to lyse and for virions carrying host DNA (the transducing particles) to be capable of infecting new host cells. A cell that has acquired a recombinant phenotype by this process is called a transductant.
KeywordsBacterial Genome Generalize Transduction Temperate Phage Helper Phage Transduce Phage
Unable to display preview. Download preview PDF.
- Campbell, A. (1977). Defective bacteriophages and incomplete prophages, pp. 259–328. In: Fraenkel-Conrat, H., Wagner, R.R. (eds.), Comprehensive Virology, vol. 8. New York: Plenum Press.Google Scholar
- Susskind, M.M., Botstein, D. (1978). Molecular genetics of bacteriophage P22. Microbiological Reviews 42: 3 85–413.Google Scholar