Tissue Engineering Techniques for Closure of Bladder Exstrophy

An Experimental Animal Model
  • Anthony Atala


The prenatal diagnosis of patients with the exstrophy-epispadias complex is now more prevalent. Prenatal ultrasonography allows for a thorough survey of fetal anatomy. The absence of bladder filling, a mass of echogenic tissue of the lower abdominal wall or a low set umbilicus during prenatal sonographic examination may suggest the diagnosis of bladder exstrophy. These findings and the presence of intraluminal intestinal calcifications suggest the presence of a cloacal malformation.


Bladder Exstrophy Lower Abdominal Wall Tissue Engineering Technique Native Bladder Fetal Anatomy 
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Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Anthony Atala
    • 1
  1. 1.Children’s Hospital and Harvard Medical SchoolBostonUSA

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