Space and Salience in Parietal Cortex

  • Keith D. Powell
  • Carol L. Colby
  • Jacqueline Gottlieb
  • Makoto Kusunoki
  • Michael E. Goldberg
Chapter

Abstract

The parietal cortex has long been thought to participate in the neural mechanisms underlying visual attention, spatial perception, and eye movements (Critchley 1953). This review will begin by describing the attentional and spatial aspects of saccadic performance in a patient with a frontoparietal deficit, and then show how single neuron activity in one particular area, the lateral intraparietal area (LIP) renders the clinical deficits understandable in neurophysiological terms.

Keywords

Receptive Field Parietal Cortex Superior Colliculus Posterior Parietal Cortex Saccade Target 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Andersen RA, Asanuma C, Cowan M(1985) Callosal and prefrontal associational projecting cell populations in area 7a of the macaque monkey: a study using retrogradely transported fluorescent dyes. J. Comp. Neurol. 232:443–455.PubMedCrossRefGoogle Scholar
  2. Baizer JS, Ungerleider LG, Desimoner R (1991) Organization of visual inputs to the inferior temporal and posterior parietal cortex in macaques. J. Neurosci. 11:168–190.PubMedGoogle Scholar
  3. Barash S, Bracewell RM, Fogassi L, Gnadt, JW, Andersen RA (1991) Saccade-related activity in the lateral intraparietal area. II. Spatial properties. J. Neurophysiol. 66:1109–1124.PubMedGoogle Scholar
  4. Burman DD, Segraves MA (1994) Primate frontal eye field activity during natural scanning eye movements. J. Neurophysiol. 71:1266–1271.PubMedGoogle Scholar
  5. Bushnell MC, Goldberg ME, Robinson DL (1981) Behavioral enhancement of visual responses in monkey cerebral cortex: I. Modulation in posterior parietal cortex related to selective visual attention. J. Neurophysiol. 46:755–772.PubMedGoogle Scholar
  6. Colby CL Duhamel J-R, Goldberg, ME (1996) Visual, presaccadic and cognitive activation of single neurons in monkey lateral intraparietal area. J. Neurophysiol. 76:2841–2852.PubMedGoogle Scholar
  7. Colby CL, Gattass R, Olson CR, Gross CG (1988) Topographic organization of cortical afférents to extrastriate visual area PO in the macaque: a dual tracer study. J. Comp. Neurol. 269:392–413.PubMedCrossRefGoogle Scholar
  8. Critchley M (1953) The Parietal Lobes. London: Edward Arnold.Google Scholar
  9. Duhamel J-R, Goldberg ME, Fitzgibbon EJ, Sirigu A, Grafman J (1992) Saccadic dysmetria in a patient with a right frontoparietal lesion: the importance of corollary discharge for accurate spatial behavior. Brain 115:1387–1402.PubMedCrossRefGoogle Scholar
  10. Goldberg ME, Bruce CJ (1990) Primate frontal eye fields. III. Maintenance of a spatially accurate saccade signal. J. Neurophysiol. 64:489–508.PubMedGoogle Scholar
  11. Goldberg ME, Bushneil M C (1981) Behavioral enhancement of visual responses in monkey cerebral cortex. II. Modulation in frontal eye fields specifically related to saccades. J. Neurophysiol. 46:773–787.PubMedGoogle Scholar
  12. Goldberg ME, Colby CL, Duhamel J-R (1990) The representation of visuomotor space in the parietal lobe of the monkey. Cold Spring Harbor Symp. Quant. Biol. 55:729–739.PubMedCrossRefGoogle Scholar
  13. Goldberg ME, Wurtz RH (1972) Activity of superior colliculus in behaving monkeys. II. Effect of attention on neuronal responses. J. Neurophysiol. 35:560–574.PubMedGoogle Scholar
  14. Gottlieb JP, Kusunoki M, Goldberg ME (1998) The representation of visual salience in monkey parietal cortex. Nature 391:481–4.PubMedCrossRefGoogle Scholar
  15. Hallett PE, Lightstone AD (1976) Saccadic eye movements to flashed targets. Vision Res. 16:107–114.PubMedCrossRefGoogle Scholar
  16. Heide W, Blankenburg M, Zimmermann E, Kompf D (1995) Cortical control of double-step saccades: implications for spatial orientation. Ann Neurol 38:739–48.PubMedCrossRefGoogle Scholar
  17. Livingstone MS, Freeman DC, Hubel, DH (1996) Visual responses in VI of freely viewing monkeys. Cold Spring Harb Symp Quant Biol 61:27–37.PubMedCrossRefGoogle Scholar
  18. Lynch JC, Graybiel AM, Lobeck, LJ (1985) The differential projection of two cytoarchitectonic subregions of the inferior parietal lobule of macaque upon the deep layers of the superior colliculus. J. Comp. Neurol. 235:241–254.PubMedCrossRefGoogle Scholar
  19. Lynch JC, McLaren JW (1989) Deficits of visual attention and saccadic eye movements after lesions of parieto-oc-cipital cortex in monkeys. J. Neurophysiol. 61:74–90.PubMedGoogle Scholar
  20. Mays LE, Sparks L (1980) Dissociation of visual and saccade-related responses in superior colliculus neurons. J. Neurophysiol. 43:207–232.PubMedGoogle Scholar
  21. Moran J, Desimone R (1985) Selective attention gates visual processing in extrastriate cortex. Science 229:782–784.PubMedCrossRefGoogle Scholar
  22. Robinson DL, Bowman EM, Kertzman C (1995) Covert orienting of attention in macaques. II. Contributions of parietal cortex. J. Neurophysiol. 74:698–712.PubMedGoogle Scholar
  23. Robinson DL, Goldberg ME, Stanton, GB Parietal association cortex in the primate: Sensory mechanisms and behavioral modulations. J. Neurophysiol. 41:910–932, 1978.PubMedGoogle Scholar
  24. Schall JD, Morel A, King DJ, Bullier, J () Topography of visual cortex connections with frontal eye field in macaque: Convergence and segregation of processing streams. J. Neurosci. 15:4464–4487, 1995.PubMedGoogle Scholar
  25. Stanton GB, Bruce CJ, Goldberg, ME () Topography of projections to posterior cortical areas from the macaque frontal eye fields. J. Comp. Neurol. 353:291–305, 1995.PubMedCrossRefGoogle Scholar
  26. Steinmetz MA, Connor CE, Constantinidis C, McLaughlin JR () Covert attention suppresses neuronal responses in area 7a of the posterior parietal cortex. J. Neurophysiol. 72:1020–1023, 1994.PubMedGoogle Scholar
  27. Stricanne B, Andersen RA, Mazzoni P (1996) Eye-centered, head-centered, and intermediate coding of remembered sound locations in area LIP. J. Neurophysiol. 76:2071–2076.PubMedGoogle Scholar
  28. Suzuki WA, Amaral DG (1994) Perirhinal and parahippocampal cortices of the macaque monkey: cortical afférents. J Comp Neurol, 350, 497–533.PubMedCrossRefGoogle Scholar
  29. Webster MJ, Bachevalier J, Ungerleider LG (1994) Connections of inferior temporal areas TEO and TE with parietal and frontal cortex in macaque monkeys. Cereb. Cortex 4:470–483.PubMedCrossRefGoogle Scholar
  30. Wurtz RH (1969) Visual receptive fields of striate cortex neurons in awake monkeys. J. Neurophysiol. 32:727–742.PubMedGoogle Scholar
  31. Yantis S, Jonides J (1984) Abrupt visual onsets and selective attention: evidence from visual search. J Exp Psychol Hum Percept Perform 10:601–21.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1999

Authors and Affiliations

  • Keith D. Powell
    • 1
  • Carol L. Colby
    • 2
  • Jacqueline Gottlieb
    • 1
  • Makoto Kusunoki
    • 1
    • 3
  • Michael E. Goldberg
    • 1
    • 4
  1. 1.Laboratory of Sensorimotor ResearchNational Eye InstituteBethesdaUSA
  2. 2.Department of Neuroscience and Center for the Neural Basis of CognitionUniversity of PittsburghPittsburghUSA
  3. 3.Department of Physiology NihonUniversity School of MedicineTokyo 173Japan
  4. 4.Department of Neurology GeorgetownUniversity School of MedicineUSA

Personalised recommendations