Mixed-Integer Nonlinear Programming Problems (MINLPs)
Mixed-integer problems are those that involve both continuous and integer variables. The introduction of integer variables allows the modeling of complex decisions through graph theoretic representations denoted as superstructures (Floudas, 1995). This representation leads to the simultaneous determination of the optimal structure of a network and its optimum operating parameters. Thus MINLPs find applications in engineering design such as heat exchanger network synthesis, reactor-separator-recycle network synthesis or pump network synthesis (Floudas, 1995; Grossmann, 1996), in metabolic pathway engineering (Hatzimanikatis et al., 1996a,b; Dean and Dervakos, 1996), or in molecular design (Maranas, 1996; Churi and Achenie, 1996) .
KeywordsHeat Transfer Coefficient Heat Exchanger Test Problem Binary Variable Global Solution
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