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Endothelial Cell Injury

  • Chapter
Minimally Invasive Cardiac Surgery

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

In conventional cardiac surgery, use of cardiopulmonary bypass (CPB) initiates a series of events best-characterized as a “whole body inflammatory response,” with activation of coagulation, fibrinolysis, and inflammatory cascades (1–3). Perturbation and activation of the endothelium are central in this response (4–6). However, with the emergence of minimally invasive techniques that allow coronary artery bypass grafts to be performed on a beating heart without CPB, it is likely that diminished acute systemic endothelial activation will result.

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Authors
  1. Talia Barzel Spanier MD
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  2. Ann Marie Schmidt MD
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Editor information

Editors and Affiliations

  1. Division of Cardiothoracic Surgery, Department of Surgery, Columbia Presbyterian Medical Center, New York, NY, USA

    Mehmet C. Oz MD  & Daniel J. Goldstein MD  & 

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© 1999 Springer Science+Business Media New York

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Spanier, T.B., Schmidt, A.M. (1999). Endothelial Cell Injury. In: Oz, M.C., Goldstein, D.J. (eds) Minimally Invasive Cardiac Surgery. Contemporary Cardiology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-3036-4_3

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  • DOI: https://doi.org/10.1007/978-1-4757-3036-4_3

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-108-0

  • Online ISBN: 978-1-4757-3036-4

  • eBook Packages: Springer Book Archive

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