Colon cancer: the potential involvement of the normal microflora

  • John Birkbeck


Adenocarcinoma of the colon is one of the commonest malignancies seen in Western countries, often vying for first place with bronchial carcinoma in the league tables. The human colon is a unique piece of anatomy, in that it contains vast quantities of living and actively metabolizing microorganisms, which play a crucial role in the health of the colonic mucosa from which adenocarcinomas are derived. Hence it is reasonable to enquire whether the nature of the activities of this microflora may influence the risk of malignancy in the colorectal area. It is further relevant to ask to what extent dietary factors, which may influence the risk of colon cancer, may act through, or be modulated by, the microflora.


Colon Cancer Bile Acid Dietary Fibre Wheat Bran Resistant Starch 
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© Springer Science+Business Media Dordrecht 1999

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  • John Birkbeck

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