Evidence-Based Transfusion Medicine: A Fundamental Part of Risk Management

  • J. Kleijnen
Part of the Developments in Hematology and Immunology book series (DIHI, volume 34)


In July 1998, the British Medical Journal published a systematic review about the effect on mortality of human albumin and plasma protein fraction (PPF) administration in the management of critically ill patients [1]. The same review was published 2 weeks earlier in the Cochrane Library. It concerned the results of about 30 randomised controlled trials comparing albumin/PPF with no albumin/PPF, or with a crystalloid solution, in critically ill patients with hypovolemia, burns, or hypoalbuminaemia.


Cochrane Review Cochrane Library Cochrane Collaboration Cochrane Control Trial Register Albumin Administration 
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Copyright information

© Springer Science+Business Media Dordrecht 1999

Authors and Affiliations

  • J. Kleijnen
    • 1
  1. 1.NHS Centre for Review and DisseminationUniversity of YorkYorkUK

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