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Flavonoid Radicals

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Free Radicals, Oxidative Stress, and Antioxidants

Part of the book series: NATO ASI Series ((NSSA,volume 296))

Abstract

Flavonoids belong to the recently popular phytochemicals (Huang, Osawa, Ho, and Rosen, 1994; Ho, Osawa, Huang, and Rosen, 1994; Manach, Régérat, Texier, Agullo, Demigné, and Rémésy, 1996), plant products with potential benefit for human health. Since the compounds exist as ubiquitous secondary plant metabolites, they are an important part of human diet (Das and Ramanathan, 1992; Hertog, Feskens, Hollman, and Katan, 1993; Ktihnau, 1976; Stavric and Matula, 1992). They are also considered as the active principles in many medicinal plants (Wollenweber, 1988; Xin, Zhao, Li, and Hou, 1990). Due to the pronounced antioxidative potential of flavonoids, there is considerable interest in the structure and reactions of the flavonoid aroxyl radicals as obligatory intermediates during radical-scavenging reactions. Indeed the preferred mechanistic interpretation of the antioxidative effect of flavonoids lies in the radical-scavenging properties of these compounds, both in model systems and under in vitro conditions (see Bors, Michel, and Saran, 1994; Bors, Heller, Michel, and Stettmaier, 1996; Rice-Evans, Miller, and Paganga, 1996).

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Authors and Affiliations

  1. Institut für Strahlenbiologie, GSF Forschungszentrum für Umwelt und Gesundheit, D-85764, Neuherberg, Germany

    Wolf Bors & Christa Michel

  2. Institut für Biochemische Pflanzenpathologie, GSF Forschungszentrum für Umwelt und Gesundheit, D-85764, Neuherberg, Germany

    Werner Heller & Heinrich Sandermann Jr.

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  1. Wolf Bors
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  2. Christa Michel
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  3. Werner Heller
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  4. Heinrich Sandermann Jr.
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  1. Akdeniz University, Antalya, Turkey

    Tomris Özben

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Bors, W., Michel, C., Heller, W., Sandermann, H. (1998). Flavonoid Radicals. In: Özben, T. (eds) Free Radicals, Oxidative Stress, and Antioxidants. NATO ASI Series, vol 296. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2907-8_8

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  • DOI: https://doi.org/10.1007/978-1-4757-2907-8_8

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