Pathophysiology of Cerebral Ischemia

Mechanisms Involved in Neuronal Damage
  • Tomris Özben
Part of the NATO ASI Series book series (NSSA, volume 296)


Stroke is a common and devastating neurological disorder (Scatton, 1994) which is the third leading cause of death in major industrialized countries and also a major cause of long-lasting disability. Cerebral ischemia is always vascular origin and can be divided into haemorrhagic and thromboembolic, with the latter accounting for approximately 90% of strokes (Scatton, 1994) and results from embolic or thrombotic occlusion of the major cerebral arteries, most often the middle cerebral artery.


Nitric Oxide NMDA Receptor Cerebral Ischemia Middle Cerebral Artery Occlusion Xanthine Oxidase 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Tomris Özben
    • 1
  1. 1.Department of BiochemistryAkdeniz University Medical FacultyAntalyaTurkey

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