Free Radicals and Antioxidants in Physical Exercise

  • José Viña
  • Miguel Asensi
  • Juan Sastre
  • José A. Ferrero
  • Emilio Servera
  • Amparo Gimeno
  • Federico Pallardó
Part of the NATO ASI Series book series (NSSA, volume 296)


The beneficial effects of exercise are well documented. Indeed, it ameliorates diabetes mellitus, improves the plasma lipid profile, increases bone density and may help to lose weight. However, as stated in the old medical saying “the beneficial effects of exercise are lost with exhaustion”. It has been known for some time that exhaustive exercise causes muscle soreness, induces an elevation of cytosolic enzyme activities in blood plasma and may be harmful. In the last decade a considerable amount of information concerning production of free radicals in exhaustive exercise has been obtained. An international symposium took place in Valencia, Spain in 1993 and a book was published on the subject (Sen, Packer, and Hanninen, 1994). This subject has been reviewed by (Bendich, 1991; and Ji, 1995). In this chapter we will summarize the present state of the art on this subject. The reader will find more information in the aforementioned sources.


Chronic Obstructive Pulmonary Disease Physical Exercise Free Radical Formation Exhaustive Exercise Glutathione Disulfide 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • José Viña
    • 1
  • Miguel Asensi
    • 1
  • Juan Sastre
    • 1
  • José A. Ferrero
    • 1
  • Emilio Servera
    • 1
  • Amparo Gimeno
    • 1
  • Federico Pallardó
    • 1
  1. 1.Departamento de FisiologiaUniversidad de ValenciaValenciaSpain

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