Abstract
As outlined in Part III, alkaloids have evolved as a chemical defense against herbivores, microorganisms, and viruses or against other plants (Chapters 11, 14, 15, and 16). Assuming an evolutionary molecular modeling, the structures of many alkaloids have been shaped through natural selection so that they can interfere with a wide variety of molecular or physiological targets of animals and microorganisms (Chapter 12).
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Major Reviews
Budavari, S., (ed.), 1989, The Merck Index, 11th ed. Merck, Rahway, NJ.
Gilman, A. G., 1991, Goodman and Gilman’s: The Pharmacological Basis of Therapeutics, 8th ed., Pergamon Press, New York.
Harborne, J. B., and Baxter, H., 1993, Phytochemical Dictionary: A Handbook of Bioactive Compounds from Plants, Taylor & Francis, London.
Reynolds, J. E. F., (ed.), 1993, Martindale—The Extra Pharmacopoeia, The Pharmaceutical Press, London.
Roth, L., Daunderer, M., and Kormann, K., 1994, Giftpflanzen Pflanzengifte, Ecomed, Landsberg/Lech.
Teuscher, E., and Lindequist, U., 1994, Biogene Gifte, Fischer Verlag, Stuttgart.
Wink, M., 1993, Allelochemical properties or the raison d’être of alkaloids, in: The Alkaloids, Vol. 43 (G. A. Cordell, ed.), Academic Press, San Diego, pp. 1–118.
Key References
Besch, H. Jr., Watanabe, A. M., 1977, Binding and effect of tritiated quinidine on cardiac subcellular enzyme systems: Sarcoplasmic reticulum vesicles, mitochondria and Na+, K+-adenosine triphosphatase. J. Pharmacol. Exp. Ther. 202, 354–364.
Capraro, H.-G., and Brossi, A., 1984, Troplonic Colchicum alkaloids, in: The Alkaloids, Vol. 23 (A. Brossi, ed.), Academic Press, San Diego, pp. 1–70.
Fujii, T., and Ohaba, M., 1983, Ipecac alkaloids and β-carboline congeners, in: The Alkaloids, Vol. 22 (A. Brossi, ed.), Academic Press, San Diego, pp. 1–50.
Rodriguez, E., Aregullin, M., Nishida, T., Uehara, S., Wrangham, R. W., Abramowski, Z., Finlayson, A., and Towers, G. H. N., 1985, Thiarubrin A, a bioactive constituent of Aspilia (Asteraceae) consumed by wild chimpanzees. Experientia 41:419–420.
Rodriguez, E., and Wrangham, R. W. 1993, Zoopharmacognosy: The use of medicinal plants by animals: in Phytochemical Potentials of Tropical Plants (K. R. Downum, J. T. Romeo, and H. A. Stafford, eds.), Plenum Press, New York, pp. 89–105.
Schmeller, T., Sauerwein, M., Sporer, F., Wink, M., and Müller, W. E., 1994, Binding of quinolizidine alkaloids to nicotinic and muscarinic acetylcholine receptors, J. Nat. Prod. 57:1316–1319.
Simeon, S., Rios, J. L., and Villar, A., 1989, Pharmacological activities of benzophenanthridine and phenanthrene alkaloids, Pharmazie 44:593–597.
Zetler, G., 1988, Neuroleptic-like, anticonvulsant, and antinociceptive effects of aporphine alkaloids: Bulbocapnine, corytuberine, boldine, glaucine, Arch. Int. Pharmacodyn. Then 296:255–281.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1998 Springer Science+Business Media New York
About this chapter
Cite this chapter
Schmeller, T., Wink, M. (1998). Utilization of Alkaloids in Modern Medicine. In: Roberts, M.F., Wink, M. (eds) Alkaloids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2905-4_18
Download citation
DOI: https://doi.org/10.1007/978-1-4757-2905-4_18
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4419-3263-1
Online ISBN: 978-1-4757-2905-4
eBook Packages: Springer Book Archive