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Nongenomic Rapid Effects of Vitamin D

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Vitamin D

Part of the book series: Nutrition and Health ((NH))

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Abstract

1α,25-Dihydroxyvitamin D3 [lα,25(OH)2D3] is the most potent vitamin D metabolite. The mechanism(s) by which the hormone alters cell growth and differentiation is largely unknown. Specific nuclear vitamin D receptors (nVDRs) for this secosteroid have been found in numerous organs and cell lines (1). The binding of 1α,25(OH)2D3 to the nVDR and subsequent binding of the hormone-receptor complex to selected DNA sequences were thought to be the mechanisms explaining all the hormone’s actions.

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  1. Daniel T. Baran
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  1. Boston University Medical Center, Boston, MA, USA

    Michael F. Holick PhD, MD

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Baran, D.T. (1999). Nongenomic Rapid Effects of Vitamin D. In: Holick, M.F. (eds) Vitamin D. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-2861-3_12

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  • DOI: https://doi.org/10.1007/978-1-4757-2861-3_12

  • Publisher Name: Humana Press, Totowa, NJ

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