Regulation of Lymphocyte Development by Microenvironmental and Systemic Factors

  • Encarnacion Montecino-Rodriguez
  • Kenneth Dorshkind
Part of the Contemporary Immunology book series (CONTIM)


Lymphocyte development is a dynamic process in which committed lymphoid precursors progress through a series of defined maturational stages before generating B- and T-cells that express immunoglobulin and the T-cell receptor (TCR), respectively (1–4). This process is regulated by a variety of increasingly well-defined extracellular signals that influence the growth and differentiation of developing lymphoid progenitors.


Stromal Cell Bone Marrow Stromal Cell Dwarf Mouse Lymphocyte Development Lymphoid Progenitor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Encarnacion Montecino-Rodriguez
  • Kenneth Dorshkind

There are no affiliations available

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