Genetic identity coefficients are powerful theoretical tools for genetic analysis. Geneticists have devised these indices to measure the degree of inbreeding of a single individual and the degree of relatedness of a pair of relatives. Since the degree of inbreeding of a single individual can be summarized by the relationship between his or her parents, we will focus on identity coefficients for relative pairs. These coefficients pertain to a generic autosomal locus and depend only on the relevant pedigree connecting two relatives and not on any phenotypes observed in the pedigree. In Chapter 6 we will investigate the applications of identity coefficients. Readers desiring motivation for the combinatorial problems attacked here may want to glance at Chapter 6 first.


Inbreeding Coefficient Cholesky Decomposition Kinship Coefficient Autosomal Locus Binomial Sampling 
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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Kenneth Lange
    • 1
  1. 1.Department of Biostatistics and MathematicsUniversity of MichiganAnn ArborUSA

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