Abstract
The treatment of pain in the elderly patient presents many challenges: their pain syndromes are often due to chronic diseases that are not curable; the metabolic and pharmacodynamic changes that accompany aging complicate the prescribing of analgesics; cognitive dysfunction confounds pain assessment; functional ability may be impaired; and psychosocial issues often need to be addressed. In short, further data are required to improve pain treatment in this population. The appropriate management of pain in the elderly is based on general principles of assessment, pharmacotherapy, and use of anesthetic, neurosurgical, and cognitive-behavioral interventions. The strategy employed includes a careful history and physical examination to define the symptom complex, the pain pathophysiology and etiology, and to pursue a diagnostic and therapeutic plan. Often, the pain can be treated by directing attention to the underlying cause, for example, replacing a fractured hip. In other instances either the cause cannot be determined or it is not amenable to medical or surgical intervention and pain management consists of treating the pain complaint with analgesics alone.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Crook J, Rideout E, Browne G. The prevalence of pain complaints in a general population. Pain. 1984; 18 (3): 299–314.
Ferrell BA, Ferrell BR. Principles of pain management in older people. Compr Ther. 1991; 17 (8): 53–58.
Sorkin BA, Rudy TE, Hanlon RB, et al. Chronic pain in old and young patients: differences appear less important than similarities. J Gerontol. 1990; 45 (2): 64–68.
Thomas MR, Roy R. Age and pain: a comparative study of the younger and older elderly. J Pain Manage. 1988; 1: 174–179.
Moss MS, Lawton, MP, Glicksman A. The role of pain in the last year of life of older persons. J Gerontol. 1991; 46 (2): 51–57.
Sternbach RA. Survey of pain in the United States: The Nuprin Pain Report. J Clin Pain. 1986; 2: 49.
Lavsky-Shulan M, Wallace RB, Kohout FJ, et al. Prevalence and functional correlates of low back pain in the elderly: the Iowa 65+ Rural Health Study. J Am Geriatr Soc. 1985; 33: 23–28.
Ferrell BA, Ferrell BR, Osterweil D. Pain in the nursing home./Am Geriatr Soc. 1990; 38: 409–414.
Roy R, Michael TA. Survey of chronic pain in an elderly population. Can Fam Physician. 1986; 32: 513.
Roberts HC, Eastood H. Pain and its control in patients with fractures of the femoral neck while awaiting surgery. Injury. 1994; 25 (4): 237–239.
Johansson C, Mellstrom D, Rosengren K, et al. Prevalence of vertebral fractures in 85-year-olds. Radiographic examination of 462 subjects. Acta Orthop Scand. 1993; 64 (l): 25–27.
Bliss MR, Schofield M. A pilot leg ulcer clinic in a geriatric day hospital. Age Ageing. 1993; 22 (4): 279–284.
Flett R, Harcourt B, Alpass F. Psychosocial aspects of chronic lower leg ulceration in the elderly. West J Nurs Res. 1994; 16 (2): 183–192.
Lindholm C, Bjellerup M, Christensen OB, et al. Quality of life in chronic leg ulcer patients. An assessment according to the Nottingham Health Profile. Acta Derm Venereol. 1993; 73 (6): 440–443.
Ciocon JO, Fernandez BB, Ciocon DG. Leg edema: clinical clues to the differential diagnosis. Geriatrics. 1993; 48 (5): 34–40.
Kay L. Prevalence, incidence and prognosis of gastrointestinal symptoms in a random sample of an elderly population. Age Ageing. 1994; 23 (2): 146–149.
Foley KM. Pain syndromes in patients with cancer. Med Clin North Am. 1987; 71 (2): 169–184.
18. Mor V. Hospice Care Systems: Structure Process Costs and Outcomes. New York: Springer; 1987.
Morris J, Mor V, Goldberg R, et al. The effect of treatment setting and patient characteristics on pain in terminal cancer patients: a report from the National Hospice Study. J Chron Dis. 1986; 39 (l): 27–35.
Morris J, Suissa S, Sherwood S, et al. Last days: a study of the quality of life of terminally ill cancer patients. J Chron Dis. 1986; 39 (l): 47–62.
McCormack A, Hunter-Smith D, Piotrowski ZH, et al. Analgesic use in home hospice cancer patients. J Fam Pract. 1992; 34 (2): 160–164.
Magni D, et al. Pain as a symptom in elderly depressed patients. Eur Arch Psychiatr Neurol Sci. 1985; 235: 143.
Mcintosh IB. Psychological aspects influence the threshold of pain. Geriatr Med. 1990; 20: 37–41.
Kennedy GJ, Kelman HR, et al. Hierarchy of characteristics associated with depressive symptoms in an urban elderly sample. Am J Psychiatry. 1989; 146: 220–225.
Parmelee PA, Katz IR, Lawton MP. The relation of pain to depression among institutionalized aged. J Gerontol. 1991; 46: 15–21.
Keefe FJ, Williams DA. A comparison of coping strategies in chronic pain patients in different age groups./Gerontol. 1990; 45 (4): 161–165.
Canellas M, Bosch F, Bassols A, et al. The prevalence of pain in hospitalized patients. Med Clin. 1993; 101 (2): 51–54.
Greenlee KK. Pain and analgesia: considerations for the elderly in critical care. AACN Clin Issues Crit Care Nurs. 1991; 2: 720–728.
Hall-Lord ML, Larsson G, Bostrom I. Elderly patients’ experiences of pain and distress in intensive care: a grounded theory study. Intensive Crit Care Nurs. 1994; 10 (2): 133–141.
Clement DG, Retchin SM, Brown RS, et al. Access and outcomes of elderly patients enrolled in managed care. JAMA. 1994; 271: 1487–1492.
Bonica J. Pain research and therapy: past and current status and future needs. In: NG LKY, Bonica JJ, eds. Proceedings of the National Conference on Pain, Discomfort and Humanitarian Care. New York: Elsivier; 1980: 1–47.
Cohen F. Postsurgical pain relief: patients’ status and nurses’ medication choices. Pain. 1980; 9: 265–274.
Brockopp DY, Warden S, Colclough G, et al. Nursing knowledge: acute postoperative pain management in the elderly. J Gerontol Nurs. 1993; 19 (ll): 31–37.
McCaffery M, Ferrell B, O’Neill-Page E, et al. Nurses’ knowledge of opioid analgesic drugs and psychological dependence. Cancer Nursing. 1990; 13 (l): 21–27.
Williams MA, Campbell EB, Raynor W Jr, et al. Predictors of acute confusional states in hospitalized elderly patients. Res Nurs Health. 1985; 8 (1): 31–40.
Williams-Russo P, Urquhart BL, Sharrock NE, et al. Post-operative delirium: predictors and prognosis in elderly orthopedic patients [see comments]. J Am Geriatr Soc. 1992; 40 (8): 759–767.
Bowen DM, Davison AN. Biochemical changes in the normal aging brain and in dementia. In: Issacs B, ed. Recent Advances in Geriatric Medicine. Edinburgh: Churchill Livingstone; 1978.
Parmelee PA, Smith B, Katz IR. Pain complaints and cognitive status among elderly institution residents. J Am Geriatr Soc. 1993; 41: 517–522.
Portenoy RK, Kanner RM. Patterns of analgesic prescription and consumption in a university-affiliated community hospital. Arch Intern Med. 1985; 145: 439.
Goldberg RJ, et al. Analgesic use in terminal cancer patients: report for the National Hospice Study. J Chron Dis. 1986; 39: 37.
Faherty BS, Grier MR. Analgesic medication for elderly people post-surgery. Nurs Res. 1984; 33: 369–372.
Harkins SW, Price DD, Martelli M. Effects of age on pain perception: thermonociception. J Gerontol. 1986; 41 (1): 58–63.
Thomson FJ, Masson EA, Boulton AJ. The clinical diagnosis of sensory neuropathy in elderly people. Diabet Med. 1993; 10: 843–846.
Kaiko RF, Wallenstein SL, Rogers AG, et al. Narcotics in the elderly. Med Clin North Am. 1982; 66: 1079–1089.
Reidenberg MM. Drugs in the elderly. Med Clin North Am. 1982; 66: 1073–1078.
Scott JC, Stanski DR. Decreased fentanyl and alfentanil dose requirements with age. A simultaneous pharmacokinetic and pharmacodynamic evaluation. J Pharmacol Exp Ther. 1987; 240 (1): 159–166.
Sengstaken EA, King SA. The problems of pain and its detection among geriatric nursing home residents./Am Geriatr Soc. 1993; 41: 541–544.
Bonica J J. The Management of Pain. 2nd ed. Philadelphia: Lea & Febiger; 1990.
Wall PD, Melzack R. Textbook of Pain. Edinburgh: Churchill-Livingstone; 1994.
IASP Subcommittee on Taxonomy Pain Terms. A list with definitions and notes on usage. Pain. 1979; 6: 249.
Herr KA, Mobily PR, Smith C. Depression and the experience of chronic back pain: a study of related variables and age differences. Clin J Pain. 1993; 9 (2): 104–114.
Galer BS, Portenoy RK. Acute herpetic and postherpetic neuralgia: clinical features and management. Mt Sinai J Med. 1991; 58 (3): 257–266.
Portenoy RK, Farkash A. Acute herpetic and postherpetic neuralgia: clinical review and current management. Ann Neurol. 1987; 20: 651.
Portenoy RK, Hagen NA. Breakthrough pain: definition and management. Oncology. 1989; 3 (suppl 8): 25–29.
Portenoy RK, Farkash A. Optimal control of non-malignant pain in the elderly. Geriatrics. 1988; 43 (5): 29.
Herr KA, Mobily PR. Chronic pain and depression. J Psychosoc Nurs Ment Health Serv. 1992; 30 (9): 7–12.
Kellgren JG. On the distribution of pain arising from deep somatic structures with charts of segmental pain areas. Clin Sci. 1939; 4: 35–46.
Foltstein MF, Foltstein SE, McHugh PR. Mini-Mental State: a practical method of grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12: 189–198.
Pfieffer E. A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J Am Geriatr Soc. 1975; 23 (10): 433–441.
Melzack R, Wall P. The Challenge of Pain. New York: Basic Books; 1983.
Keefe F, Bradley L. Behavioral and psychological approaches to the assessment and treatment of chronic pain. Gen Hosp Psychiatry. 1984; 6 (l): 49–54.
Melzack R. The McGill Pain Questionnaire: major properties and scoring methods. Pain. 1975; 1: 277–299.
Melzack R. The short-form McGill Pain Questionnaire. Pain. 1987; 30: 191–197.
Herr KA, Mobily PR. Pain assessment in the elderly. Clinical considerations. J Gerontol Nurs. 1991; 17 (4): 12–19.
Herr KA, Mobily PR. Comparison of selected pain assessment tools for use with the elderly. Appl Nurs Res. 1993; 6 (l): 39–46.
Barsky AJ, Frank CB, Cleary PD, et al. The relation between hypochondriasis and age. Am J Psychiatry. 1991; 148: 923–928.
Middaugh SJ, Levin RB, Kee WG, et al. Chronic pain: its treatment in geriatric and younger patients. Arch Phys Med Rehabil. 1988; 69: 1021–1026.
Cutler RB, Fishbain DA, Rosomoff RS, et al. Outcomes in treatment of pain in geriatric and younger age groups. Arch Phys Med Rehabil. 1994; 75 (4): 457–464.
Cohen JL. Pharmacokinetic changes in aging. Am J Med. 1886; 80 (5A): 31–38.
Morgan J, Furst DE. Implications of drug therapy in the elderly. Clin Rheum Dis. 1986; 12: 227–244.
Geokas MC, Haverback BJ. The aging gastrointestinal tract. Am J Surg. 1969; 117: 881–892.
Goldberg PB, Roberts J. Pharmacologic basis for developing rational drug regimens for elderly patients. Med Clin North Am. 1983; 67: 315–331.
Bender AD. The effect of increased age on the distribution of peripheral blood flow in man. J Am Geriatr Soc. 1965; 13: 192.
Bender AD. Pharmacodynamic principles of drug therapy in the aged. J Am Geriatr Soc. 1974; 22 (7): 296–303.
Rafsky HA, Newman B. Liver function test in the aged. The serum cholesterol partition, bromsulphalein, cephalin flocculation and oral and intravenous hippuric acid test. Am J Digest Dis. 1965; 10: 66.
Schlegel SE, Paulus H. Non-steroidal and analgesic therapy in the elderly. Clin Rheum Dis. 1986; 12: 245.
Ciabattoni G, Cinotti G, Pierucci A, et al. Effects of sulindac and ibuprofen in patients with chronic glomerular disease: evidence for the dependence of renal function on prostacyclin. N Engl J Med. 1984; 310: 279–283.
Whelton A, Stout R, Spilman P, et al. Renal effects of ibuprofen, piroxicam, and sulindac in patients
with asymptomatic renal failure: a prospective, randomized, crossover comparison. Ann Intern Med. 1990; 112:568–576.
Belleville JW, et al. Influence of age on pain relief from analgesics. JAMA. 1971; 217: 1835.
Kaiko RF. Age and morphine analgesia in cancer patients with postoperative pain. Clin Pharmacol Ther. 1980; 28: 823–826.
Helmers H, Van Peer A, Woestenborghs R, et al. Alfentanil kinetics in the elderly. Clin Pharmacol Ther. 1984; 36 (2): 239–243.
Simons LA, Tett S, Simons J, et al. Multiple medication use in the elderly. Use of prescription and nonprescription drugs in an Australian community setting. MedJAust. 1992; 157 (4): 242–246.
Forbes JA, Butterworth GA, Burchfield WH, et al. Evaluation of ketorolac, aspirin, and an acetaminophen-codeine combination in postoperative oral surgery pain. Pharmacotherapy. 1990; 9 (5): 322–330.
Perneger TV, Whelton PK, Klag MJ. Risk of kidney failure associated with the use of acetaminophen, aspirin, and nonsteroidal antiinflammatory drugs [see comments]. N Engl J Med. 1994; 331 (25): 1675–1679.
Sager DS, Bennett RM. Individualizing the risk/benefit ratio of NSAIDs in older patients. Geriatrics. 1992; 47 (8): 24–31.
Brooks PM, Day RO. Nonsteroidal antiinflammatory drugs—differences and similarities [published erratum appears in N Engl J Med. 1991;325:747] [see comments]. N Engl J Med. 1991; 324: 1716–1725.
Graham D, White RH, Moreland LW, et al. Duodenal and gastric ulcer prevention with Misoprostol in arthritis patients taking NSAIDS. Ann Intern Med. 1993; 119: 257.
Ferrer-Brechner T, Ganz P. Combination therapy with ibuprofen and methadone for chronic cancer pain. Am J Med. 1984; 77 (lA): 78–83.
Houde RW, et al. Evaluation of analgesics in patients with cancer pain. In: Lasagna L, ed. International Encyclopedia of Pharmacology and Therapeutics. Vol. 1. New York: Pergamon; 1966: 59.
Beaver WT, Feise G. Comparison of the analgesic effects of morphine, hydroxyzine, and their combination in patients with postoperative pain. In: Bonica JJ, ed. Advances in Pain Research and Therapy. Vol. 1. New York: Raven Press; 1976: 553–557.
Forrest W Jr, Brown B Jr, Brown CR, et al. Dextroamphetamine with morphine for the treatment of postoperative pain. N Engl J Med. 1977; 296: 712–715.
Bruera E, Brenneis C, Paterson AH, et al. Narcotics plus methylphenidate (Ritalin) for advanced cancer pain. Am J Nurs. 1988; 88: 1555–1556.
Bruera E, Brenneis C, Paterson AH, et al. Use of methylphenidate as an adjuvant to narcotic analgesics in patients with advanced cancer. J Pain Symptom Manage. 1989; 4 (l): 3–6.
Bruera E, Chadwick S, Brenneis C, et al. Methylphenidate associated with narcotics for the treatment of cancer pain. Cancer Treat Rep. 1987; 71 (l): 67–70.
Foley KM, Macaluso C. Adjuvant analgesic drugs in cancer pain management. In: Aronoff GM, ed. Evaluation and Treatment of Chronic Pain. 2nd ed. Baltimore: Williams & Wilkins; 1992: 340.
Watson CRN, et al. Amitriptyline vs placebo in postherpetic neuralgia. Neurology. 1982; 32: 671.
Getto CJ, Sorkness CA, Howell T. Antidepressants and chronic nonmalignant pain: a review. J Pain Symptom Manage. 1987; 2: 9–18.
Weinberg DS, et al. Sublingual absorption of selected opioid analgesics. Clin Pharmacol Ther. 1988; 44: 335.
Coyle N. Continuous subcutaneous infusions of opiates in cancer patients with pain. Oncol Nurs Forum. 1986; 13: 53.
Portenoy RK, et al. Intravenous infusions of opioids in cancer pain: clinical review and guidelines for use. Cancer- Treat Rep. 1986; 70: 575.
Cousins MJ, Mather LE. Intrathecal and epidural administration of opioids. Anesthesiology. 1984; 61 (3): 276–310.
Coyle N, Foley KM. The use of multiple routes of opioid drug administration in an advanced cancer patient. J Pain Symptom Manage. 1993; 8 (4): 234–237.
Galer BS, Coyle N, Pasternak GW, et al. Individual variability in the response to different opioids: report of five cases. Pain. 1992; 49: 87–91.
Cherny N, Chang V, Ingham J, et al. [Abstract] The prevalance and outcomes of sequential trials of opioid analgesics in management of cancer pain. Presented at the 12th Annual Scientific meeting of the American Pain Society, Orlando, FL, 1993.
Bruera E, Schoeller T, Montejo G. Organic hallucinosis in patients receiving high doses of opiates for cancer pain. Pain. 1992; 48: 397–399.
Bruera E, Macmillan K, Hanson J, et al. The cognitive effects of the administration of narcotic analgesics in patients with cancer pain. Pain. 1989; 39: 13–16.
Porter J, Jick H. Addiction rare in patients treated with narcotics [letter]. N Engl J Med. 1980; 302 (2): 123.
Foley KM. Clinical tolerance to opioids. In: Basbaum A, Besson JM, eds. Towards a New Pharmacotherapy of Pain. Chichester: Wiley; 1991: 181.
Travell J, Simons D. Myofascial Pain and Dysfunction: The Trigger Point Manual. Baltimore: Williams and Wilkins; 1983.
Nashold B. Current status of the DREZ operation. Neurosurgery. 1984; 15: 942–944.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Springer Science+Business Media New York
About this chapter
Cite this chapter
Hewitt, D.J., Foley, K.M. (1997). Pain and Pain Management. In: Cassel, C.K., et al. Geriatric Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-2705-0_57
Download citation
DOI: https://doi.org/10.1007/978-1-4757-2705-0_57
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4757-2707-4
Online ISBN: 978-1-4757-2705-0
eBook Packages: Springer Book Archive