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Developmental Considerations

The Fetal and Neonatal Endocrine Response to Stress

  • Chapter
Endocrinology of Critical Disease

Part of the book series: Contemporary Endocrinology ((COE,volume 4))

Abstract

The morphologic and physiologic bases for an endocrine response to critical illnesses, which is an important adaptive mechanism for homeostatic balance and recovery during postnatal life, are established during fetal development and in many instances become competent prior to birth. This chapter will explore the structural and functional development of several key elements of the endocrine system during intrauterine life and in infancy. Although clearly of importance in homeostasis and response to illness, the endocrine pancreas, parathyroid, and gastrointestinal hormone systems will not be addressed herein. Additionally, development and regulation of the gonads, which are adversely impacted by many illnesses, will not be discussed since their responses do not appear to be of critical importance to survival in serious illnesses. Rather, emphasis will be placed on the development of hypothalamic endocrine control, the anterior and posterior pituitary, adrenal cortex, adrenal medulla, and thyroid.

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Parker, C.R. (1997). Developmental Considerations. In: Ober, K.P. (eds) Endocrinology of Critical Disease. Contemporary Endocrinology, vol 4. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-2584-1_2

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  • DOI: https://doi.org/10.1007/978-1-4757-2584-1_2

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