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Spleen

  • Ralph H. Hruban
  • William H. Westra
  • Timothy H. Phelps
  • Christina Isacson

Abstract

Three elements are essential for the thorough dissection of the spleen: (1) Be familiar with the patient’s clinical history. The dissection of a spleen removed for trauma is very different from the dissection of a spleen removed for a hematopoietic malignancy; (2) Remember that fresh tissue for immunophenotypic and genetic studies may be necessary to classify hematopoietic neoplasms involving the spleen; and (3) Sections of the spleen for histology need to be very thinly sliced and well fixed.

Keywords

Fresh Tissue Surgical Pathology White Pulp Hematopoietic Malignancy Splenic Trauma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Burke JS. Surgical pathology of the spleen: an approach to the differential diagnosis of splenic lymphomas and leukemias. Part 1. Diseases of the white pulp. Am J Surg Pathol. 1981; 5: 551–563.PubMedCrossRefGoogle Scholar
  2. Burke JS. Surgical pathology of the spleen: an approach to the differential diagnosis of splenic lymphomas and leukemias. Part II. Diseases of the red pulp. Am j Surg Pathol. 1981; 5: 681–694.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Ralph H. Hruban
    • 1
  • William H. Westra
    • 1
  • Timothy H. Phelps
    • 2
  • Christina Isacson
    • 3
  1. 1.Department of Pathology Meyer 7-181The Johns Hopkins HospitalBaltimoreUSA
  2. 2.Department of Art as Applied to Medicine, School of MedicineThe Johns Hopkins UniversityBaltimoreUSA
  3. 3.Department of PathologyVirginia Mason Medical CenterSeattleUSA

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