Brain and Spinal Cord

  • Peter C. Burger


In some respects, pathologic evaluation of specimens from the central nervous system (CNS) is less complicated than evaluation of other organs, because requests for margins and the need for extensive specimen dissections are unusual. On the other hand, CNS specimens are usually small, and care must be taken to preserve the tissue. Do not use all of the tissue by freezing the entire specimen. This is especially true for specimens of the spinal cord. These can be minute, yet major therapeutic decisions often depend on the results of the pathology studies. In all cases, it is essential to keep the clinical and radiological findings in mind when processing specimens from the CNS.


Freeze Section Formic Acid Solution Cytological Preparation Needle Biopsy Specimen Surgical Pathology Report 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bell JE, Ironside JW. How to tackle a possible Creutzfeldt-Jakob disease necropsy. J Clin Pathol. 1993; 46: 193–197.PubMedCrossRefGoogle Scholar
  2. Brown P. Guidelines for high risk autopsy cases: special precautions for Creutzfeldt-Jakob disease. In: Hutchins GM, ed. Autopsy Performance and Reporting. Northfield, Ill: College of American Pathologists; 1990; 68–74.Google Scholar
  3. Burger PC, Scheithauer BW. Atlas of Tumor Pathology: Tumors of the Central Nervous System, 3rd series, fascicle 10. Washington, DC: Armed Forces Institute of Pathology; 1994.Google Scholar
  4. Burger PC, Scheithauer BW, Vogel SF. Surgical Pathology of the Nervous System and Its Coverings. New York, NY: Churchill Livingstone; 1991.Google Scholar
  5. Scheithauer BW. Surgical pathology of the pituitary: the adenomas. Pathol Annu. 1984; 19: 317–374.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Peter C. Burger

There are no affiliations available

Personalised recommendations