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Preparation, Characterization, and Utilization of Biomimetic Membranes

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Biofunctional Membranes

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Abstract

Biological membranes define the very existence of the living cell and are intimately involved in in vivo syntheses, recognition, information transfer, and energy transduction.1 Self-organization, predominantly bimolecular thickness, domain formation, temperature, media- and electrical signal-dependent fluidity, and permeability control are believed to be responsible for the effectiveness of the biological membrane in mediating these myriads of activities. The exploitation of biomembranedependent processes in vitro in relatively simple artificial biomimetic membranes for the compartmentalization of substrates, for acting as carriers, and for altering reaction rates, products, and stereochemistries has been the subject of intensive research activities.2 Biomimetic membranes are defiined by a utilitarian point of view as compartments which are able to. accommodate selected substrates in desired microenvironments. Aqueous micelles, reversed micelles, monolayers, Langmuir-Blodgett (LB) films, bilayer lipid membranes (BLMs), freely suspended ultrathin fiilms, surfactant vesicles (liposomes), cast multilayers, self-assembled films, and even such layered compounds as zeolites and pillared clays (or organoclay complexes) are considered to be biomimetic membranes in this broad definition. In contrast, the term biofunctional membrane is limited to an “entity in which biological molecules (or cells) are attached to polymeric supports cast in the form of porous membranes.”3

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  1. Department of Chemistry, Syracuse University, Syracuse, New York, 13244-4100, USA

    Janos H. Fendler

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  1. University of Kentucky, Lexington, Kentucky, USA

    D. Allan Butterfield

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Fendler, J.H. (1996). Preparation, Characterization, and Utilization of Biomimetic Membranes. In: Butterfield, D.A. (eds) Biofunctional Membranes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2521-6_7

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  • DOI: https://doi.org/10.1007/978-1-4757-2521-6_7

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