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Biomaterials in Vascular Surgery

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Abstract

The development of materials to replace or bypass diseased arterial segments has facilitated substantial advances in vascular surgery over the last 40 yr. Porous cloth tubes were first introduced as an arterial substitute in 1952 by Voorhees and colleagues (1). Five years later Edwards and Tapp fabricated bifurcated aortic grafts of braided nylon that were crimped to prevent kinking (2). Newer synthetic prostheses have enabled successful reconstructions in large-diameter, high-flow vessels, such as the aorta and its primary intrathoracic and abdominal branches. In medium-sized (<6mm diameter) and small-diameter arteries (<4mm) bypass or replacement with long segments of textile grafts have results in unacceptable lower long-term patency rates. Small vessel reconstructions presently rely on the use of autogenous veins for coronary artery and below-knee femoropopliteal lesions and for microvascular repair of digital and cerebral vessels. Better determination of the characteristics influencing biomaterial function will allow development of low-flow prostheses for small diameter arteries and venous reconstruction.

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Back, M.R., White, R.A. (1996). Biomaterials in Vascular Surgery. In: Wise, D.L., Trantolo, D.J., Altobelli, D.E., Yaszemski, M.J., Gresser, J.D. (eds) Human Biomaterials Applications. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-2487-5_12

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