Genetic Alterations in Lung Cancer

  • Stephen J. Lemon
  • Anita L. Sabichi
  • Michael J. Birrer
Part of the Contemporary Biomedicine book series (CB, volume 12)


Lung cancer is a major cause of cancer incidence in the United States, accounting for an estimated 172,000 new cases in 1994 (Boring et al., 1994). Lung cancer incidence in males is second only to prostate cancer, and in females, it is second only to breast cancer (Miller et al., 1992a). Unfortunately, despite recent advances in oncologic therapy, survival from lung cancer remains poor, as indicated by an overall 5-yr relative survival rate of 13% (Miller et al., 1992a). As a result, lung cancer is the chief cause of cancer mortality in both men and women, accounting for an estimated 153,000 cancer deaths in 1994 (Boring et al., 1994). Further, lung cancer is likely to remain a leading cause of both cancer incidence and cancer mortality well into the next century (Gaffney et al., 1988).


Lung Cancer NSCLC Cell Line NSCLC Tumor Lung Cancer Development SCLC Cell Line 
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© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Stephen J. Lemon
  • Anita L. Sabichi
  • Michael J. Birrer

There are no affiliations available

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