Genetics of Temperate Bacteriophages
For all bacteriophages discussed in the preceding chapters, a successful phage infection always results in the immediate production of progeny virions. However, many bacteriophages are known for which there is an alternative outcome to phage infection. Instead of the customary unrestrained DNA replication and phage assembly, there is a temperate response in which a bacteriophage sets up housekeeping within a bacterial cell and maintains a stable relationship with that cell and all its progeny for many generations. The varied ways in which the temperate response can be accomplished are the subject of this chapter. The population dynamics of temperate and lytic viruses and their hosts have been analyzed by Stewart and Levin and are not covered here. The physical properties of the temperate bacteriophages discussed in this chapter are summarized in Table 8–1.
KeywordsPhage Particle Temperate Phage Lytic Infection Helper Phage Integration Host Factor
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