Abstract
The pulmonary circulation undergoes major morphological changes at birth and during adaptation to extra-uterine life (Haworth, 1988, Haworth & Hislop, 1981). It has recently been appreciated that this vascular remodelling is accompanied by major changes in the pharmacological reactivity of the large arteries (Liu et al., 1992). It is unknown to what extent these changes could be caused by alterations of K+-channels, which have emerged as an important mechanism in the control of vascular tone (Nelson et al., 1991, Standen et al. 1989, Weston & Edwards, 1991).
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Boels, P.J., Tulloh, R.M., Haworth, S.G. (1994). K +(ATP) Channels in Neonatal Pulmonary Vessels during Normal Development and Chronic Hypoxia. In: Halpern, W., Bevan, J., Brayden, J., Dustan, H., Nelson, M., Osol, G. (eds) The Resistance Arteries. Experimental Biology and Medicine, vol 26. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4757-2296-3_20
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DOI: https://doi.org/10.1007/978-1-4757-2296-3_20
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