Abstract
The genus Fusobacterium includes several species of obligately anaerobic, nonsporeforming, motile or nonmotile, Gram-negative rods. Some are slender, spindle-shaped bacilli, others are pleomorphic rods with parallel sides and rounded ends. Their habitat is the mucous membranes of humans and animals.
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Literature Cited
Aalbaek, B. 1972. Gram-negative anaerobes in the intestinal flora of pigs. Acta Vet. Scand. 13: 228–237.
Abe, P. M., C. J. Kendall, L. R. Stauffer, and J. W. Holland. 1979. Hemolytic activity of Fusobacterium necrophorum culture supernatants due to presence of phospholipase A and lysophospholipase. Am. J. Vet. Res. 40: 9296.
Adriaans, B., and B. S. Drasar, 1987. The isolation of fusobacteria from tropical ulcers. Epidem. Infect. 99: 361372.
Adriaans, B., and H. Shah. 1988. Fusobacterium ulcerans sp. nov. from tropical ulcers. Int. J. Syst. Bacteriol. 38: 447–448.
Altshuler, A., and S. Hyde. 1985. Fusobacteria. An important cause of chorioamnionitis. Arch. Pathol. Lab. Med. 109: 739–743.
Aranki, A., S. A. Syed, E. B. Kenney, and R. Freter. 1969. Isolation of anaerobic bacteria from human gingiva and mouse cecum by means of a simplified glove box procedure. Appl. Microbiol. 17: 568–576.
Baird-Parker, A. C. 1957. Isolation of Leptotrichia buccalis and Fusobacterium species from oral material. Nature 180: 1056–1057.
Bang, B. 1890–1891. Om aarsagen til lokal nekrose. Maanedskrift for Dyrlaeger 2: 235–259.
Barker, H. A., J. M. Kahn, and L. Hedrick. 1982. Pathway of lysine degradation in Fusobacterium nucleatum. J. Bacteriol. 152: 201–207.
Bartlett, J. G., V. L. Sutter, and S. M. Finegold. 1974. Anaerobic pleuropulmonary disease: Clinical observations and bacteriology in 100 cases, p. 327–344. In: A. Balows, R. M. DeHaan, V. R. Dowell, Jr., and L. B. Guze (ed.), Anaerobic bacteria: role in disease. Charles C. Thomas, Springfield, IL.
Beerens, H., M. M. Castel, and L. Fievez. 1962. Classification des Bacteroidaceae, p. 120. Abstr V III Int. Congress Microbiol., Montreal.
Beerens, H., and M. M. Tahon-Castel. 1965. Infectiones humaines à bactéries anaérobies non toxigénes. Presses Académiques Européennes, Brussels.
Berg, J. N., and R. W. Loan. 1975. Fusobacterium necrophorum and Bacteroides melaninogenicus as etiologic agents of footrot in cattle. Am. J. Vet. Res. 36: 1115–1122.
Berg, J. N., and C. M. Scanlan. 1982. Studies of Fusobacterium necrophorum from bovine hepatic abscesses: Biotypes, quantitation, virulence, and antibiotic susceptibility. Am. J. Vet. Res. 43: 1580–1586.
Beveridge, W. I. B. 1941. Foot rot in sheep: A transmissible disease due to infection with Fusiformis nodosus (n.sp.). Council for Scientific and Industrial Research, Commonwealth of Australia, Bulletin 140, Melbourne.
Bowden, G. H., and J. M. Hardie. 1971. Anaerobic organisms from the human mouth, p. 177–205. In: D. A. Shapton and R. G. Board (ed.), Isolation of anaerobes. Society for Applied Bacteriology Technical Series No. 5. Academic Press, London.
Brams, J., I. Pilot, and D. J. Davis. 1923. Studies of fusiform bacilli and spirochetes. II. Their occurrence in normal preputial secretions and in erosive and gangrenous balanitis. J. Infect. Dis. 32: 159–166.
Breed, R. S., E. G. D. Murray, and N. R. Smith (ed.). 1957. Bergey’s manual of determinative bacteriology, 7th ed. Williams & Wilkins, Baltimore.
Brook, I. 1986. Encapsulated anaerobic bacteria in synergistic infections. Microbiol. Rev. 50: 452–457.
Brook, I. 1988. Recovery of anaerobic bacteria from clinical specimens in 12 years at two military hospitals. J. Clin. Microbiol. 26: 1181–1188.
Brook, I., and R. I. Walker. 1986. The relationship between Fusobacterium species and other flora in mixed infection. J. Med. Microbiol. 21: 93–100.
Cameron, G. R., and F. E. Williams. 1926. An epidemic affecting stock rabbits. J. Pathol. Bacteriol. 29: 185–188.
Castellani, A., and A. J. Chalmers. 1919. Manual of tropical medicine. William Wood & Company, Baltimore.
Cato, E. P., L. V. H. Moore, and W. E. C. Moore. 1985. Fusobacterium alocis sp. nov. and Fusobacterium sulci sp. nov. from the human gingival sulcus. Int. J. Syst. Bacteriol. 35: 475–477.
Clark, B. L., D. J. Stewart, and D. L. Emery. 1985. The role of Fusobacterium necrophorum and Bacteroides melanino-genicus in the aetiology of interdigital necrobacillosis in cattle. Aust. Vet. J. 62: 47–49.
Coyle-Dennis, J. E., and L. H. Lauerman. 1978. Biological and biochemical characteristics of Fusobacterium necrophorum leukocidin. Am. J. Vet. Res. 39: 1790–1793.
Coyle-Dennis, J. E., and L. H. Lauerman. 1979. Correlations between leukocidin production and virulence of isolates of Fusobacterium necrophorum. Am. J. Vet. Res. 40: 274–276.
Dack, G. M., L. R. Dragstedt, and T. E. Heinz. 1937. Further studies on Bacterium necrophorum isolated from cases of chronic ulcerative colitis. J. Infect. Dis. 60: 335355.
Dack, G. M., T. E. Heinz, and L. R. Dragstedt. 1935. Ulcerative colitis. Study of bacteria in the isolated colons of three patients by cultures and by inoculation of monkeys. Arch. Surg. 31: 225–240.
Davis, D. J., and I. Pilot. 1922. Studies of Bacillus fusiformis and Vincent’s spirochete. I. Habitat and distribution of these organisms in relation to putrid and gangrenous processes. J. Amer. Med. Ass. 79: 944–951.
Dehazya, P., and R. J. Coles, Jr. 1980. Agglutination of human erythrocytes by Fusobacterium nucleatum: factors influencing hemagglutination and some characteristics of the agglutinin. J. Bacteriol. 143: 205–211.
Egerton, J. R., and D. S. Roberts. 1971. Vaccination against ovine foot-rot. J. Comp. Pathol. 81: 179–185.
Egerton, J. R., D. S. Roberts, and I. M. Parsonson. 1969. The aetiology and pathogenesis of ovine foot-rot. I.A histological study of the bacterial invasion. J. Comp. Pathol. 79: 207–216.
Eggerth, A. H., and B. H. Gagnon. 1933. The bacteroides of human feces. J. Bacteriol. 25: 389–413.
Ellermann, V. 1904. Über die Kultur der fusiformen Bacillen. Cbl Bakteriol. Parasiten. Infektkr. Abt. I Orig. 37: 729–730.
Emery, D. L. 1988. Approaches to identify and neutralize virulence determinants of Fusobacterium and Bacteroides spp. p. 343–362. In: J. A. Roth (ed.), Virulence mechanisms of bacterial pathogens. American Society for Microbiology, Washington D.C.
Emery, D. L., and J. A. Vaughan. 1986. Generation of immunity against Fusobacterium necrophorum in mice inoculated with extracts containing leucocidin. Vet. Microbiol. 12: 255–268.
Fales, W. H., and G. W. Teresa. 1972a. A selective medium for the isolation of Sphaerophorus necrophorus. Am. J. Vet. Res. 33: 2317–2321.
Fales, W. H., and G. W. Teresa. 1972b. Fluorescent antibody technique for identifying isolates of Sphaerophorus necrophorus of bovine hepatic abscess origin. Am. J. Vet. Res. 33: 2323–2329.
Fales, W. H., J. F. Warner, and G. W. Teresa. 1977. Effects of Fusobacterium necrophorum leukotoxin on rabbit peritoneal macrophages in vitro. Am. J. Vet. Res. 38: 491–495.
Falkler, W. H., Jr., and C. E. Hawley. 1977. Hemagglutinating activity of Fusobacterium nucleatum. Infect. Immun. 15: 230–238.
Feiner, J. M., and V. R. Dowell, Jr.. 1971. “Bacteroides” bacteremia. Am. J. Med. 50: 787–796.
Fievez, L. 1963. Etude comparée des souches de Sphaerophorus necrophorus isolées de L’homme et chez L’animal. Monographie, Presses Académiques Européennes, Brüssel.
Finegold, S. 1977. Anaerobic bacteria in human disease. Academic Press, New York.
Finegold, S. M., H. R. Attebery, and V. L. Sutter. 1974. Effect of diet on human fecal flora: Comparison of Japanese and American diets. Am. J. Clin. Nutr. 27: 14561469.
Finegold, S. M., D. J. Flora, H. R. Attebery, and V. L. Sutter. 1975. Fecal bacteriology of colonic polyp patients and control patients. Cancer Res. 35: 3407–3417.
Foglesong, M. A., D. L. Cruden, and A. J. Markovetz. 1984. Pleomorphism of fusobacteria isolated from the cockroach hindgut. J. Bacteriol. 158: 474–480.
Fuller, R., and M. Lev. 1964. Quantitative studies on some of the Gram-negative anaerobic bacteria in the pig alimentary tract. J. Appl. Bacteriol. 27: 434–438.
Gainer, R. S. 1983. Necrobacillosis in wildebeest calves. J. Wildlife Dis. 19: 155–156.
Garcia, M. M., D. C. Alexander, and K. A. McKay. 1975a. Biological characterization of Fusobacterium necrophorum cell fractions in preparation for toxin and immunization studies. Infect. Immun. 11: 609–616.
Garcia, M. M., K. M. Charlton, and K. A. McKay. 1975b. Characterization of endotoxin from Fusobacterium necrophorum. Infect. Immun. 11: 371–379.
Gharbia, S. E. 1987. A biochemical approach to the study of the genus Fusobacterium. Ph.D. Dissertation. The University of Kuwait.
Gharbia, S. E., and H. N. Shah. 1988a. Glucose utilization and growth response to protein hydrolysates by Fuso-bacterium species. Curr. Microbiol. 17: 229–234.
Gharbia, S. E., and H. N. Shah. 1988b. Characteristics of glutamate dehydrogenase, a new diagnostic marker of the genus Fusobacterium. J. Gen. Microbiol. 134: 327332.
Gharbia, S. E., H. N. Shah, and S. G. Welch. 1989. The influence of peptides on the uptake of amino acids in Fusobacterium; predicted interactions with Porphyromonas gingivalis. Curr. Microbiol. 19: 231–235.
Gorbach, S. L., K. B. Menda, H. Thadepalli, and L. Keith. 1973. Anaerobic microflora of the cervix in healthy women. Am. J. Obst. Gyn. 117: 1053–1055.
Graham, N. P. H., and J. R. Egerton. 1968. Pathogenesis of ovine foot-rot: The role of some environmental factors. Aust. Vet. J. 44: 235–240.
Griffin, M. H. 1970. Fluorescent antibody techniques in the identification of Gram-negative nonsporeforming anaerobes. Hlth Lab. Sci. 7: 78–83.
Hadi, A. W., and C. Russel. 1969. Fusiforms in gingival material. Quantitative estimations from normal individuals and cases of periodontal disease. Brit. Dent. J. 126: 83–84.
Hamp, E. G., and S. E. Mergenhagen. 1963. Experimental intracutaneous fusobacterial and fusospirochetal infections. J. Infect. Dis. 112: 84–99.
Hardie, J. M., and G. H. Bowden. 1974. The normal flora of the mouth, p. 47–83. In: E A. Skinner and J. G. Can (ed.), The normal microbial flora of man. Society for Applied Bacteriology Symposium Series No. 3. Academic Press, London.
Henry, S., A. DeMaria, Jr., and W. R. McCabe. 1983. Bacteremia due to Fusobacterium species. Am. J. Med. 75: 225–231.
Hill, G. B., S. Osterhout, and P. C. Pratt. 1974. Liver abscess production by nonsporeforming anaerobic bacteria in a mouse model. Infect. Immun. 9: 599–603.
Hite, K. E., H. C. Hesseltine, and L. Goldstein. 1947. A study of the bacterial flora of the normal and pathological vagina and uterus. Am. J. Obst. Gyn. 53: 233240.
Hofstad, T., and T. Kristoffersen. 1971. Preparation and chemical characteristics of endotoxic lipopolysaccharide from three strains of Sphaerophorus necrophorus. Acta Pathol. Microbiol. Scand., Sect B 79: 383–390.
Holdeman, L. V., E. P. Cato, and W. E. C. Moore. 1977. Anaerobe laboratory manual. 4th ed., Blacksburg. VPI Anaerobe Laboratory, Virginia Polytechnic Institute and State University, VA.
Holdeman, L. V., I. J. Good, and W. E. C. Moore. 1976. Human fecal flora: Variation in bacterial composition within individuals and a possible effect of emotional stress. Appl. Environ. Microbiol 31: 359–376.
Horne, H. 1898–1899. Renens klovsyge. Nor. Vet. tidsskr. 10–11: 97–110.
Hurst, V. 1957. Fusiformis in the infant mouth. J. Dent. Res. 36: 513–515.
Hussein, H. E., and M. T. A. Shigidi. 1974. Isolation of Sphaerophorus necrophorus from bovine liver abscess in the Sudan. Trop. An. Hlth. 6: 253–254.
Ishii, T., M. Kanoe, T. Inoue, K. Kai, and H. Blobel. 1988. Cytotoxic effects of a leukocidin from Fusobacterium necrophorum on bovine hepatic cells. Med. Microbiol. Immunol. 177: 27–32.
Jensen, C. O. 1913. Die vom Nekrosebacillus (Bacillus necroseos) hervorgerufenen Krankheiten, p. 234–250. In: Kolle, W., and von Wassermann, A. (ed.), Handbuch der pathogenen Mikroorganismen, vol. 6. Gustav Fischer Verlag, Jena.
Jensen, R., J. Flint, and L. A. Griner. 1954. Experimental hepatic necrobacillosis in beef cattle. Am. J. Vet. Res. 15: 5–14.
Jensen, R., and D. R. MacKay. 1965. Diseases of feedlot cattle. Lea & Febiger, Philadelphia.
Kanoe, M., H. Imagawa, M. Toda, A. Sato, M. Inoue, and Y. Yoshimoto. 1976. Bacteriology of bovine hepatic abscesses. Jpn. J. Vet. Sci. 38: 263–268.
Kaufman, E. J., P. A. Mashimo, E. Hausmann, C. T. Hanks, and S. A. Ellison. 1972. Fusobacterial infection. Enhancement by cell free extracts of Bacteroides melaninogenicus possessing collagenolytic activity. Arch. Oral Biol. 17: 577–580.
Knorr, M. 1923. Uber die fusospirilläre Symbiose, die Gattung Fusobacterium (K. B. Lehmann) und Spirillum sputigenum. II. Mitteilung. Die Gattung Fusobacterium. Zbl. Bakteriol. Parasitenk. Infektkr. Abt. 1 Orig. 89: 4–22.
Krygier, G., R. J. Genco, R A. Mashimo, and E. Hausmann. 1973. Experimental gingivitis in Macaca speciosa monkeys: Clinical, bacteriological and histological similarities to human gingivitis. J. Periodontol. 44: 454–463.
Langworth, B. F. 1977. Fusobacterium necrophorum: Its characteristics and role as animal pathogen. Bacteriol. Rev. 44: 373–390.
Lemierre, A. 1936. On certain septicaemias due to anaerobic organisms. Lancet ii: 701–703.
Lewis, K. H., and L. F. Rettger. 1940. Non-sporulating anaerobic bacteria of the intestinal tract. J. Bacteriol. 40: 287–307.
Lewkowicz, X. 1901. Recherches sur la flore microbienne de la bouche des nourrissons. Arch. Med. Exp. 13: 633660.
Loeffler, F. 1884. Bacillus der Kälberdiphterie. Mittheilungen aus dem Kaiserlichen Gesundheitsamte 2: 493–499.
Loesche, W. J. 1969. Oxygen sensitivity of various anaer-obic bacteria. Appl. Microbiol. 18: 723–727.
Love, D. N., E. P. Cato, J. L. Johnson, R. F. Jones, and M. Bailey. 1987. Deoxyribonucleic acid hybridization among strains of fusobacteria isolated from soft tissue infections of cats: comparison with human and animal type strains from oral and other sites. Int. J. Syst. Bacteriol. 37: 23–26.
Love, D. N., R. F. Jones, and M. Bailey. 1980. Characterization of Fusobacterium species isolated from soft tissue infections in cats. J. Appl. Bacteriol. 48: 325–331.
McCarthy, C., M. L. Snyder, and R. B. Parker. 1965. The indigenous oral flora of man. I. The newborn to the 1year-old infant. Arch. Oral Biol. 10: 61–70.
McClung, L. J., and R. Toabe. 1947. The egg yolk plate reaction for the presumptive diagnosis of Clostridium sporogenes and certain species of the gangrene and botulinum groups. J. Bacteriol. 53: 139–147.
Maier, B. R., M. A. Flynn, G. C. Burton, R. K. Tsukakawa, and D. J. Hentges. 1974. Effects of a high-beef diet on bowel flora: A preliminary report. Am. J. Clin. Nutr. 27: 1470–1474.
Mettam, R. W. M., and J. Carmichael. 1933. Necrobacillosis in recently captured antelope in Uganda. J. Comp. Pathol. 46: 16–24.
Miller, W. D. 1889. Die Mikroorganismen der Mundhöhle. Die örtlichen and allgemeinen Erkrankungen welche durch dieselben hervorgerufen werden. Georg Thieme Verlag, Leipzig.
Moore, W. E. C. 1966. Techniques for routine culture of fastidious anaerobes. Int. J. Syst. Bacteriol. 16: 173–190.
Moore, W. E. C., and L. V. Holdeman. 1974a. Genus II Fusobacterium. Knorr 1922.4, p. 404–416. In: R. E. Buchanan, and N. E. Gibbons (ed.), Bergey’s manual of determinative bacteriology, 8th ed. The Williams and Wilkins Company, Baltimore.
Moore, W. E. C., and L. V. Holdeman. 1974b Human fecal flora: The normal flora of 20 Japanese-Hawaiians. Appl. Environ. Microbiol. 27: 961–979.
Moore, W. E. C., L. V. Holdeman, E. P. Cato, M. Smibert, J. A. Burmeister, and R. R. Ranney. 1983. Bacteriology of moderate (chronic) periodontitis in mature adult humans. Infect. Immun. 42: 510–515.
Moore, W. E. C., L. V. Holdeman, R. M. Smibert, D. E Hash, J. A. Burmeister, and R. R. Ranney. 1982. Bacteriology of seven periodontitis in young adults human. Infect. Immun. 38: 1137–1148.
Moore-Gillon, J., T. M. Lee, S. J. Eykyn, and I. Philips. 1984. Necrobacillosis: a forgotten disease. Brit. Med. J. 288: 1526–1527.
Morgenstein, A. A., D. M. Citron, and S. M. Finegold. 1981. New medium selective for Fusobacterium species and differential for Fusobacterium necrophorum. J. Clin. Microbiol. 13: 666–669.
Nagai, S., M. Kanoe, and M. Toda. 1984. Purification and partial characterization of Fusobacterium necrophorum hemagglutins. Zbl. Bakteriol. A258: 232–241.
Newsom, I. E. 1938. A bacteriologic study of liver absceses in cattle. J. Infect. Dis. 63: 232–233.
Nolechek, W. E 1918. Necrobacillosis in horses and mules. J. Am. Vet. Med. Ass. 54: 150–155.
Ohtani, E. 1970a. Selective media for the isolation of Gram-negative anaerobic rods. Jpn. J. Bacteriol. 25: 222–232.
Ohtani, F. 1970b. Selective media for the isolation of Gram-negative anaerobic rods. Part II. Distribution of Gram-negative anaerobic rods in feces of normal human beings. Jpn. J. Bacteriol. 25: 292–299.
Oliphant, J. C., R. Parsons, and G. R. Smith. 1984. Aetiological agents of necrobacillosis in captive wallabies. Res. Vet. Sci. 36: 382–384.
Ornata, R. R., and M. N. Disraely. 1956. A selective me- dium for oral fusobacteria. J. Bacteriol. 72: 677–680.
Onderdonk, A. B., J. G. Bartlett, T. Louie, N. Sullivan-Seig1er, and S. L. Gorback. 1976. Microbial synergy in experimental intra-abdominal abscess. Infect. Immun. 13: 22–26.
Panel Report. 1973. Foot rot among cattle. Modern Vet. Practice 54: 63–65.
Parsonson, I. M., J. R. Egerton, and D. S. Roberts. 1967. Ovine interdigital dermatitis. J. Comp. Pathol. 77: 309313.
Peach, S., F. Fernandez, K. Johnson, and B. S. Drasar. 1974. The nonsporing anaerobic bacteria in human faeces. J. Med. Microbiol. 7: 213–221.
Plaut, H. C. 1894. Studien zur Bakteriellen Diagnostik der Diphterie und der Anginen. Dtsch Med. Wschr. 20: 920–923.
Porschen, R. K., and S. Sonntag. 1974. Extracellular deoxyribonuclease production by anaerobic bacteria. Appl. Microbiol. 27: 1031–1033.
Pratt, J. S. 1927. On the biology of B. fusiformes. J. Infect. Dis. 41: 461–466.
Prévot, A. R. 1938. Études de systématique bactérienne. III. Invalidité du genre Bacteroides. Castellani et Chalmers. Demembrement et reclassification. Ann. Inst. Pasteur 60: 285–307.
Prévot, A. R., P. Goret, L. Joubert, P. Tardieux, and N. Aladame. 1951. Recherches bactériologiques sur une infection purulente d’allure actinomycosique chez le chat. Ann. Inst. Pasteur 81: 85–88.
Pribram, E. 1929. A contribution to the classification of microorganisms. J. Bacteriol. 18: 361–394.
Richardson, R. L., and M. Jones. 1958. A bacteriolytic cen- sus of human saliva. J. Dent. Res. 37: 697–709.
Roberts, D. S. 1967a. The pathogenic synergy of Fusiformis necrophorus and Corynebacterium pyogenes. I. Influence of the leucocidal exotoxin of F. necrophorus. Brit. J. Exp. Pathol. 48: 665–673.
Roberts, D. S. 1967b. The pathogenic synergy of Fusiformis necrophorus and Corynebacterium pyogenes. II. The response of F. necrophorus to a filterable product of C. pyogenes. Brit. J. Exp. Pathol. 48: 674–679.
Roberts, D. S., and J. R. Egerton. 1969. The aetiology and pathogenesis of ovine foot-rot. II The pathogenic association of Fusiformis nodosus and F. necrophorus. J. Comp. Pathol. 79: 217–227.
Roberts, D. S., N. P. H. Graham, J. R. Egerton, and I. M. Parsonson. 1968. Infective bulbous necrose (heel abscess) of sheep, a mixed infection with Fusiformis necrophorus and Corynebacterium pyogenes. J. Comp. Pathol. 78: 9–17.
Robinson, D. A., and R. J. Hay. 1985. Tropical ulcer in Zambia. Trans. Roy. Soc. Trop. Med. Hyg. 80: 132–137.
Robrish, S. A., C. Oliver, and J. Thomson. 1987. Amino acid-dependent transport of sugar by Fusobacterium nucleatum ATCC 10953. J. Bacteriol. 169: 3891–3897.
Samuel, J. L. 1983. Jaw disease in macropod marsupials: Bacterial flora isolated from lesions and from the mouths of affected animals. Vet. Microbiol. 8: 373–387.
Scanlan, C. M., J. N. Berg, and W. H. Fales. 1982. Cornparative in vitro leukotoxin production of three bovine strains of Fusobacterium necrophorum. Am. J. Vet. Res. 43: 1329–1333.
Schmorl, G. 1891. Über ein pyogenes Fadenbacterium (Streptothrix cuniculi). Dsch. Z. Tiermed. Pathol. 17: 375–408.
Sebald, M. 1962. Étude sur les bactéries anaérobies gram-négatives asporulées. University of Paris. Dissertation.
Shimada, K., K. S. Bricknell, and S. M. Finegold. 1969. De-conjugation of bile acids by intestinal bacteria: Review of literature and additional studies. J. Infect. Dis. 119: 273–281.
Shinjo, T., and H. Kiyoyma. 1986. Pathogenicity of a nonhaemagglutinating mutant strain of Fusobacterium necrophorum biovar A in mice. Jpn J. Vet. Sci. 48: 523527.
Simon, P. C. 1975. A simple method for rapid identification of Sphaerophorus necrophorus isolates. Can. J. Comp. Med. Vet. Sci. 39: 349–353.
Simon, P. C., and P. L. Stovell. 1969. Diseases of animals associated with Sphaerophorus necrophorus: characteristics of the organism. Vet. Bull. 39: 311–315.
Simon, P. C., and P. L. Stovell. 1971. Isolation of Sphaero phorus necrophorus from bovine hepatic abscesses in British Columbia. Can. J. Comp. Med. Vet. Sci. 35: 103–106.
Slanetz, L. W., and L. F. Rettger. 1933. A systematic study of the fusiform bacteria. J. Bacteriol. 26: 599–617.
Slots, J., and T. V. Potts. 1982. Fusobacterium simiae, a new species from monkey dental plaque. Int. J. Syst. Bacteriol. 32: 191–194.
Slots, J., T. V. Potts, and P. A. Mashimo. 1983. Fusobacterium periodonticum, a new species from the human oral cavity. J. Den. Res. 62: 960–963.
Smith, L. D. 1975. The pathogenic anaerobic bacteria, 2nd ed. p. 62–63. In: A. Balows (ed.), American lectures in clinical microbiology. Charles C. Thomas, Springfield, IL
Spaulding, E. H., and L. E Rettger. 1937. The Fusobacterium genus. I. Biochemical and serological clasification. J. Bacteriol. 34: 535–548.
Stauffer, L. R., E. O. Hill, J. W. Holland, and W. A. Altemeier. 1975. Indirect fluorescent antibody procedure for the detection and identification of Bacteroides and Fusobacterium in clinical specimens. J. Clin. Microbiol. 2: 337–344.
Stewart, D. J., B. L. Clark, J. E. Peterson, D. A. Griffiths, and E. E Smith. 1982. Importance of pilus-associated antigen in Bacteroides nodosus vaccines. Res. Vet. Sci. 32: 140–147.
Sutter, V. L., D. M. Citron, M. A. C. Edelstein, and S. M. Finegold. 1985. Wadsworth anaerobic bacteriology manual, 4th. ed. Star Publishing Company, Belmont, CA.
Sutter, V. L., P. T. Sugihara, and S. M. Finegold. 1971. Rifampin-blood-agar as a selective medium for the isolation of certain anaerobic bacteria. Appl. Microbiol. 22: 777–780.
Sveen, K., T. Hofstad, and K. C. Milner. 1977. Lethality for mice and chick embryos, pyrogenicity in rabbits and ability to gelate lysates from amoebocytes of Limulus polyphemus by lipopolysaccharides from Bacteroides, Fusobacterium and Veillonella. Acta Pathol. Microbiol. Scand. Sect. B 85: 388–396.
Syed, S. A. 1972. Biochemical characteristics of Fusobacterium and Bacteroides species from mouse cecum. Can. J. Microbiol. 18: 169–174.
Terada, A., K. Uchida, and T. Mitsuoka. 1976. Die Bacteroidaceenflora in den Faeces von Schweinen. Zbl. Bakteriol. Parasitenk. Infektkr. Hyg. Orig. A 234: 362370.
Tissier, H. 1905. Répartition des microbes dans l’intestin du nourrison. Ann. Inst. Pasteur 19: 109–123.
Trust, T. J., L. M. Bull, B. R. Currie, and J. T. Buckley. 1979. Obligate anaerobic bacteria in the gastrointestinal microflora of the grass carp (Ctenopharyngodon idella), goldfish (Carassius auratus), and rainbow trout (Salmo gairdneri). J. Fish. Res. Board Can. 36: 1174–1179.
Ueno, K., P. T. Sugihara, K. S. Brichnell, H. R. Attebery, V. L. Sutter, and S. M. Finegold. 1974. Comparison of characteristics of Gram-negative anaerobic bacilli isolated from feces of individuals in Japan and the United States, p. 135–148. In: A. Balows, R. M. DeHaan, V. R. Dowell Jr., and L. B. Guze (ed.), Anaerobic bacteria: Role in disease. Charles C Thomas, Springfield, IL.
van Assche, F. F., and A. T. Wilssens. 1977. Fusobacterium perfoetens (Tissier) Moore and Holdeman 1973: Description and proposed neotype strains. Int. J. Syst. Bacteriol. 27: 1–5.
van Houte, J., and R. J. Gibbons. 1966. Studies of the cultivable flora of normal human feces. Antonie van Leeuwenhoek J. 32: 212–222.
Veillon, A., and A. Zuber. 1898. Recherches sur quelques microbes strictement anaérobies et leur rôle en pathologie. Arch. Med. Exp. 10: 517–545.
Vincent, H. 1896. Sur l’étiologie et sur les lesions anatomopathologique de la pourriture d’Hôpital. Ann. Inst. Pasteur 10: 488–510.
Vincent, H. 1899. Recherches bactériologiques sur l’angine a Bacillus fusiformis. Ann. Inst. Pasteur 13: 609–620.
Vincent, H. 1904. Étiologie de la stomatite ulcéro-membraneuse primitive. Compt. Rend. Soc. Biol. ( Paris ) 56: 311–313.
Wahren, A., K. Bernholm, and T. Holme. 1971. Formation of proteolytic activity in continuous culture of Sphaerophorus necrophorus. Acta Pathol. Microbiol. Scand. Sect. B 79: 391–398.
Wahren, A., and Holme, T. 1973. Amino acid and peptide requirement of Fusiformis necrophorus. Bacteriol. 116: 279–284.
Walker, C. B., D. Ratlitt, D. Muller, R. Mandell, and S. S. Socransky. 1979. Medium for selective isolation of Fusobacterium nucleatum from human periodontal pockets. J. Clin. Microbiol. 10: 844–849.
Warner, F., W. H. Fales, M. C. Sutherland, and G. W. Teresa. 1975. Endotoxin from Fusobacterium necrophorum of bovine hepatic abscess origin. Am. J. Vet. Res. 36: 1015–1019.
Weinberg, M., R. Nativelle, and A. R. Prévot. 1937. Les microbes anaérobies. Masson et Cie, Paris.
Weiss, J. E., and L. F. Rettger. 1937. The Gram-negative bacteroides of the intestine. J. Bacteriol. 33: 423–434.
Werner, H. 1972a. A comparative study of 55 Sphaerophorus strains. Differentiation of 3 species: Sphaerophorus necrophorus, Sph. varius and Sph. freundii. Med. Microbiol. Immunol. 157: 299–314.
Werner, H. 1972b. Anaerobierdifferenzierung durch gaschromatographische Stoffwechselanalysen. Zbl Bakteriol. Parasitenk. Infektkr. Hyg. Orig. A 220: 446–451.
Werner, H., F. Neuhaus, and H. Hussels. 1971. A biochemical study of fusiform anaerobes. Med. Microbiol. Immunol. 157: 10–16.
Werner, H., and G. Pulverer. 1971. Haufigkeit und medizinische Bedeutung der eiterregenden Bacteroides and Sphaerophorus-arten. Dsch. Med. Wschr. 96: 13251329.
Williams, B. L., R. M. Pantalone, and J. C. Sherris. 1976. Subgingival microflora and periodontitis. J. Periodont. Res. 11: 1–18.
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Hofstad, T. (1992). The Genus Fusobacterium. In: Balows, A., Trüper, H.G., Dworkin, M., Harder, W., Schleifer, KH. (eds) The Prokaryotes. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-2191-1_75
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