Biomaterials pp 223-244 | Cite as

Tissue Response to Implants

  • Joon B. Park
  • Roderic S. Lakes


In order to implant a material, the surgeon has to injure the tissue first. Also the injured or diseased tissues should be removed to some extent in the process of implantation. The success of the entire operation depends on the kind and degree of tissue response. This is an important aspect of biocompatibility. Biocompatibility entails mechanical, chemical, pharmacological, and surface compatibility as mentioned in Chapter 1. The tissue response toward injury may vary widely according to the site, species, contamination, etc. However, the inflammation and the cellular response to the wound for both intentional and accidental injuries are the same regardless of the sites.


Bone Cement Tissue Reaction Tissue Response Pyrolytic Carbon Injured Site 
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Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Joon B. Park
    • 1
  • Roderic S. Lakes
    • 1
  1. 1.The University of IowaIowa CityUSA

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