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Immunology and Infectious Disease

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Geriatric Medicine

Abstract

Immunologic function declines with age. Indeed, most physiologic functions decline with age. Why, then, has so much attention been given to the study of immunologic changes in elderly humans and laboratory animals? Immunologic function probably is the most intensively studied physiologic process in gerontology. Part of the reason has to do with the rapid growth in all aspects of immunologic research in the past 3 decades. In addition, immunocytes (lymphocytes, monocytes, and polymorphonuclear leukocytes) are the most easily obtained tissue specimens in humans. A tube of venous blood provides the immunologist with millions of cells with which to study antibody production, cytotoxicity, proliferation, migration, and other characteristics that are necessary for the continued health and survival of an organism.

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Authors
  1. Edith A. Burns
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  2. James S. Goodwin
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Editors and Affiliations

  1. Section of General Internal Medicine, The University of Chicago Medical Center, 60637, Chicago, Illinois, USA

    Christine K. Cassel M.D. (Chief) (Chief)

  2. Journal of the American Medical Association, 60610, Chicago, Illinois, USA

    Donald E. Riesenberg M.D. (Senior Editor, Clinical Associate Professor of Medicine) (Senior Editor, Clinical Associate Professor of Medicine)

  3. Pritzker School of Medicine, University of Chicago, 60637, Chicago, Illinois, USA

    Donald E. Riesenberg M.D. (Senior Editor, Clinical Associate Professor of Medicine) (Senior Editor, Clinical Associate Professor of Medicine)

  4. Department of Medicine, Pritzker School of Medicine, University of Chicago, 60637, Chicago, Illinois, USA

    Leif B. Sorensen M.D., Ph.D. (Associate Chief) (Associate Chief)

  5. Geriatric Medicine, Portland V.A. Medical Center, 97207, Portland, Oregon, USA

    John R. Walsh M.D. (Chief) (Chief)

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Burns, E.A., Goodwin, J.S. (1990). Immunology and Infectious Disease. In: Cassel, C.K., Riesenberg, D.E., Sorensen, L.B., Walsh, J.R. (eds) Geriatric Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-2093-8_25

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