Abstract
The microcirculation of the kidney is unique. Most organs are relatively homogeneously prefused by arteries and veins that are interconnected by a capillary bed that supplies oxygen and nutrients to the tissue. In contrast, the perfusion of the kidney is highly heterogeneous. Tissue blood flows range from 700 ml • min-1 • 100g-1 of tissue in the renal cortex to around 50 ml • min-1 • 100g-1 of tissue in the renal papilla [1–5]. Moreover, there are structural differences in the microvasculature in various regions of the kidney, and each region contains specialized vascular structures that serve the excretory function of the kidney [6, 7]. In this regard, the renal vasculature not only supplies the metabolic needs of the tissue, but it also ultrafilters solutes and water into the tubular system, reabsorbs tubular fluid, preserves the osmotic gradient in the renal medulla, and regulates tubular function by influencing the composition of, and the hydrostatic pressure in, the renal interstitium.
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Roman, R.J. (1990). Renal Blood Flow. In: Shepherd, A.P., Öberg, P.Å. (eds) Laser-Doppler Blood Flowmetry. Developments in Cardiovascular Medicine, vol 107. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2083-9_16
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DOI: https://doi.org/10.1007/978-1-4757-2083-9_16
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