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G Protein-Linked Receptors in the Thyroid

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Control of the Thyroid Gland

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 261))

Abstract

The binding of hormones to membrane receptors results in the activation of intracellular effector(s) such as enzymes or ion channels, which in turn induce a cellular response. In thyroid cells, as in many other cells, growth and differentiation as well as specialized functions such as iodide fluxes and thyroglobulin synthesis are regulated in the above general manner. This chapter is intended to provide an analysis of the types of receptors which in thyroid cells effect this regulation, and of their mechanism of action, with a special emphasis on the role of GTP binding proteins.

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Author information

Authors and Affiliations

  1. Istituto di Ricerche Biomediche e Farmacologiche “Mario Negri”, Consorzio Mario Negri Sud, 66030, S. Maria Imbaro Chieti, Italy

    Daniela Corda, Cinzia Bizzarri, Maria Di Girolamo, Salvatore Valitutti & Alberto Luini

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  1. Daniela Corda
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  2. Cinzia Bizzarri
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  3. Maria Di Girolamo
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  4. Salvatore Valitutti
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  5. Alberto Luini
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Editors and Affiliations

  1. University of Göteborg, Göteborg, Sweden

    Ragnar Ekholm

  2. National Institutes of Health, Bethesda, Maryland, USA

    Leonard D. Kohn  & Seymour H. Wollman  & 

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Corda, D., Bizzarri, C., Di Girolamo, M., Valitutti, S., Luini, A. (1989). G Protein-Linked Receptors in the Thyroid. In: Ekholm, R., Kohn, L.D., Wollman, S.H. (eds) Control of the Thyroid Gland. Advances in Experimental Medicine and Biology, vol 261. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2058-7_9

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  • DOI: https://doi.org/10.1007/978-1-4757-2058-7_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-2060-0

  • Online ISBN: 978-1-4757-2058-7

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