G Protein-Linked Receptors in the Thyroid

  • Daniela Corda
  • Cinzia Bizzarri
  • Maria Di Girolamo
  • Salvatore Valitutti
  • Alberto Luini
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 261)


The binding of hormones to membrane receptors results in the activation of intracellular effector(s) such as enzymes or ion channels, which in turn induce a cellular response. In thyroid cells, as in many other cells, growth and differentiation as well as specialized functions such as iodide fluxes and thyroglobulin synthesis are regulated in the above general manner. This chapter is intended to provide an analysis of the types of receptors which in thyroid cells effect this regulation, and of their mechanism of action, with a special emphasis on the role of GTP binding proteins.


Muscarinic Receptor Adenylyl Cyclase Phorbol Myristate Acetate Pertussis Toxin Thyroid Cell 
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Daniela Corda
    • 1
  • Cinzia Bizzarri
    • 1
  • Maria Di Girolamo
    • 1
  • Salvatore Valitutti
    • 1
  • Alberto Luini
    • 1
  1. 1.Istituto di Ricerche Biomediche e Farmacologiche “Mario Negri”Consorzio Mario Negri SudS. Maria Imbaro ChietiItaly

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