Selective Incorporation of Eicosapentaenoic Acid in Position 2 of Plasma Triglycerides after a Dietary Supply of 2 Eicosapentaenoyl Glyceride in Man
The chemical form of polyunsaturated fatty acids (PUFA) in dietary sources is an essential determinant for their absorption and bio-availability. For example, we recently showed in man that enteral absorption of eicosapentaenoic acid (EPA) is higher and rapid when EPA is ingested as free fatty acid or triglyceride but is low when EPA is ingested as ethylester (1). This result was recently confirmed (2). Moreover, the ingestion of a synthetic triglyceride carrying EPA in position two, 1,3-dioctanoyl-2-eicosapentaenoyl glycerol (2EPA) is followed by a high incorporation of EPA in plasma triglycerides (1).
KeywordsEicosapentaenoic Acid Plasma Triglyceride Pancreatic Lipase Porcine Pancreatic Lipase Free Fatty Acid Fraction
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