Male Rat Specific Alpha2uGlobulin Nephropathy and Renal Tumourigenesis
Weinbren [see 1] characterised spontaneously occurring hyaline droplets in the otherwise normal mature male rat kidney. The ultrastructural characteristics of the spontaneous PCT hyaline body was characterised by Maunsbach as a phagolysosomal protein reabsorption droplet and defined as a male rat specific increased size and propensity for crystalloid change in comparison to the female rat or higher species, including humans .
KeywordsTestosterone Diesel Cytosol Mannitol Triad
Unable to display preview. Download preview PDF.
- 1.Mehlman, M.A., Hemstreet, C.P., Thorpe, J.J. and Weaver, N.K. (1984) [Editors] Renal Effects of Petroleum Hydrocarbon, Princeton Scientific Publishers, Princeton.Google Scholar
- 6.Kanerva, R.L., McCracken, M.S., Alden, C.L., and Stone, L.C.: Morphogenesis of decalin-induced renal alterations in the male rat. Fd. Chem. Toxic. 25:52–61, 1987.Google Scholar
- 8.Kanerva, R.L., Ridder, G. M., Lefever, F.R., and Alden, C.L.: Comparison of short-term renal effects due to oral administration of decalin or cl-limonene in young adult male Fischer-344 rats. Fd. Chem. Toxic. 1987.Google Scholar
- 9.Kanerva, R.L., and Alden, C.L.: Review of kidney sections from a subchronic d-limonene oral dosing study conducted by the National Cancer Institute. Fd. Chem. Toxic, 1987.Google Scholar