Nephrotoxicity pp 217-220 | Cite as

Effect of Furosemide and Verapamil on Gentamicin Nephrotoxicity

  • H. Nakahama
  • M. Horio
  • T. Moriyama
  • Y. Fukuhara
  • Y. Orita
  • T. Kamada

Abstract

While furosemide (F), a potent loop diuretic, has been known to potentiate gentamicin (G) nephrotoxicity (1), verapamil (V), a calcium entry blocker, has been postulated to attenuate gentamicin nephrotoxicity (2). We have therefore examined the effect of furosemide or verapamil co-administration with gentamicin on renal gentamicin accumulation.

Keywords

Renal Cortex Proximal Tubular Cell Calcium Entry Blocker Aminoglycoside Nephrotoxicity Proximal Tubular Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • H. Nakahama
    • 1
  • M. Horio
    • 1
  • T. Moriyama
    • 1
  • Y. Fukuhara
    • 1
  • Y. Orita
    • 1
  • T. Kamada
    • 1
  1. 1.First Department of MedicineOsaka University Medical SchoolFukushima-ku, Osaka 553Japan

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