Renal Haemodynamics and Renin Response During Acute Hypercapnea in Dogs
Renal haemodynamics are related to the amount of carbon dioxide inhaled. In respiratory acidosis 5% CO2 inhalation increases renal blood flow (RBF) and renal plasma flow (RPF), whereas RBF and RPF decreased after inhalation of 15% CO2. Recently, it was found that plasma renin activity (PRA) increased during acute respiratory acidosis. The PRA levels increased during both 5% CO2 and 15% CO2 inhalation (1). An extensive literature has developed concerning renin-angiotensin control systems. Three major factors, the intrarenal baroreceptors, the macula densa and the sympathetic nervous system are capable of altering renin secretion under given experimental condition.
KeywordsPlasma Renin Activity Renal Blood Flow Renal Plasma Flow Respiratory Acidosis Renin Release
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