A Mutation That Hinders The GTP Induced Aminoacyl-tRNA BINDING of ELONGATION Factor TU
Elongation factor Tu (EF-Tu) is a member of the guanine-nucleotide binding protein family. This group of proteins include translational factors1, the ras gene family2, and signal transducing proteins3. Guanine-nucleotide binding proteins exhibit diverse functions but possess common structural elements. Comparing the peptide sequences of these proteins reveals several regions with remarkable amino acid sequence similarity4–6. These regions have been ascribed to the guanine-nucleotide binding domains4–6.
KeywordsPyruvate Kinase Guanine Nucleotide Trypsin Digestion Crude Lysate Complex Dissociation
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