Abstract
Most of the extracellular signal substances (neurotransmitters, hormones, autacoids, etc) interact with particular receptor sites on the plasma membrane of mammalian cells that produce intracellular signals (or second messengers) in response to these first messengers. The membrane receptor systems are now known to be mostly composed of three protein components, i.e., receptors, transducers and the effectors that are enzymes or ion channels directly or indirectly responsible for the generation of second messengers. All the transducers so far identified are guanine-nucleotide binding proteins currently abbreviated as G proteins.
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Ui, M., Katada, T. (1989). Behavior of Membrane Guanine-Nucleotide Binding Proteins as Signal Transducers. In: Bosch, L., Kraal, B., Parmeggiani, A. (eds) The Guanine — Nucleotide Binding Proteins. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2037-2_32
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DOI: https://doi.org/10.1007/978-1-4757-2037-2_32
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