Mutations at the RAS2 Locus that, in a ras1- Background, Impair the Growth of Yeast on Nonfermentable Carbon Sources

  • Ottavio Fasano
  • Jean Bernard Crechet
  • Emmanuele De Vendittis
  • Regina Zahn
  • Georg Feger
  • Alessandra Vitelli
  • Andrea Parmeggiani

Abstract

The proteins encoded by the RAS1 and RAS2 genes (collectively denominated RAS) are important for progression of S. cerevisiae through the cell cycle. In fact, yeast cells in which the function of the RAS2 protein is constitutively activated by a point mutation cannot properly arrest in Gl (Toda et al., 1985). On the other hand, cells with a disrupted RAS1 gene and with a temperature-sensitive RAS2 gene product are found prevalently as unbudded, G1-arrested cells upon temperature shift-up (De Vendittis et al., 1986).

Keywords

Yeast Strain Adenylate Cyclase Adenylate Cyclase Activity RAS2 Protein Complete Synthetic Medium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Ottavio Fasano
    • 2
  • Jean Bernard Crechet
    • 2
  • Emmanuele De Vendittis
    • 1
  • Regina Zahn
    • 1
  • Georg Feger
    • 1
  • Alessandra Vitelli
    • 1
  • Andrea Parmeggiani
    • 2
  1. 1.Differentiation Programme, European Molecular Biology LaboratoryHeidelbergGermany
  2. 2.Laboratoire de Biochimie, Ecole PolytechniquePalaiseau-CedexFrance

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