Perspectives on the Biology of Growth Factors

  • Irving B. Fritz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 234)


In this introduction to the “Symposium on the Biology of Growth Factors”, I shall offer perspectives gained from insights provided by classical endocrinology.


Granulosa Cell Sponge Cell Specific Protein Kinase Porcine Granulosa Cell Local Growth Factor 
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  1. Doughaday, W. H., 1985, Prolactin and Growth in Health and Disease, in: “Contemporary Endocrinology,” S. H. Ingbar, ed., Plenum Publishing Corp., N.Y. Vol. 2: 27.CrossRefGoogle Scholar
  2. Fell, P. E., 1974, Porifera, in: “Reproduction of Marine Invertebrates,” A. C. Giese, and J. S. Pearse, eds., Academic Press, N.Y. Vol. 1: 51.Google Scholar
  3. Fritz, I. B., 1986, Reflections on the evolution of the regulation of spermatogenesis, Prog. Clin. Biol. Res., 226: 371.Google Scholar
  4. Hammond, J. M., and English H. F., 1987, Regulation of deoxyribonucleic acid synthesis in cultured porcine granulosa cells by growth factors and hormones, Endocrinol., 120: 1039.CrossRefGoogle Scholar
  5. Heldin, D. H., and Westermark, B., 1984, Growth factors. Mechanisms of action and relations to oncogenes, Cell, 37: 9.Google Scholar
  6. Hsu, C-J., and Hammond, J. M., 1987, Gonadotropins and estradiol stimulate immunoreactive insulin-like growth factor-I production by porcine granulosa cells in vitro, itrn, Endocrinol; 120: 198.CrossRefGoogle Scholar
  7. King, G. L., and Kahn, C. R., 1985, Effect of insulin on growth in vivo and cells in culture, in: “Control of Animal cell Proliferation,” A. L. Boynton, and H. L. Leffert, eds., Academic Press Inc., N.Y. Vol. 1: 204.Google Scholar
  8. Pilkis, S. J., Regen, D. M., Stewart, B. H., Chrisman, T., Pilkis, J., Kountz, P., Pate, T., McGrane, M., El-Maghrabi, M. R., and Claus, T., 1984, Rat liver 6-phosphofructo 2-kinase/fructose 2.6-bisphosphatose: A unique bifunctional enzyme regulated by cyclic AMP-dependent phosphorylation, in: “Enzyme Regulation by Reversible Phosphorylation-Further Advances,” P. Cohen, ed., Elsevier Science Publishers B.V., N.Y. Pp. 95–122.Google Scholar
  9. Rechler, M. M., and Nissley, S. P., 1985, The nature and regulation of the receptors for insulin-like growth factors, Ann. Rev-Physiol., 47: 425.Google Scholar
  10. Salmon, W. D., and Daughaday, W. H., 1987, A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro, J. Lab Clin. Med., 49: 825.Google Scholar
  11. Tepperman, J., and Tepperman, H. M. 1987, “Metabolic and Endocrine Physiology,” Year Book Medical Publishers, Inc., N.Y., Fifth edition. Pp. 29–42.Google Scholar
  12. Willmer, E. N., 1970, “Cytology and Evolution,” Academic Press, N.Y., 2nd edition.Google Scholar

Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Irving B. Fritz
    • 1
  1. 1.Banting and Best Dept. of Med. Res.University of TorontoTorontoCanada

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