Abstract
Renal and vascular damage, including blood pressure elevation, is often involved in complications of diabetic pregnancy. Therefore, sensitive methods for measuring elevated urinary protein excretion, especially of albumin (so-called microalbuminuria) [1–3], might be useful in early prediction of complications in diabetic as well as nondiabetic pregnancy. This is the case in nonpregnant diabetics [3–9], in whom microalbuminuria is a sensitive marker of generalized subclinical vascular disturbance and damage [6] and in whom it predicts overt nephropathy [3–6] as well as proliferative retinopathy [7]. This chapter deals with the pattern of urinary albumin excretion rate in diabetic pregnancy as studied with a sensitive radioimmunoassay for albumin using 24-h urine samples. Patients with overt nephropathy are discussed in chapter 28.
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References
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Klebe JG, Mogensen CE: Microalbuminuria in diabetic pregnancy: a marker of complications, including intrauterine death. (Submitted for publication, 1987.)
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Mogensen, C.E., Klebe, J.G. (1988). Microalbuminuria and Diabetic Pregnancy. In: Mogensen, C.E. (eds) The Kidney and Hypertension in Diabetes Mellitus. Topics in Renal Medicine, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1974-1_27
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DOI: https://doi.org/10.1007/978-1-4757-1974-1_27
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-1976-5
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