Abstract
Diabetic nephropathy is a well-described entity and increased blood pressure or established hypertension is an early finding in the course of this complication [1, 2], which is characterized by proteinuria and linear decline in glomerular filtration rate (GFR). The presence of high blood pressure superimposed on diabetes represents an additional risk factor in insulin-dependent diabetes mellitus (IDDM) patients [3]. Furthermore, the blood pressure level seems to hasten the rate of progression of renal disease [2], and effective anti-hypertensive therapy can slow the progression rate of overt diabetic nephropathy [2, 4, 5], but unfortunately even optimal antihypertensive treatment, when started in this late stage of nephropathy, cannot stop the decline in GFR but only postpone the development of the uremic stage.
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References
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© 1988 Springer Science+Business Media Dordrecht
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Christensen, C.K. (1988). The Concept of Incipient Diabetic Nephropathy and the Longitudinal Course of Microalbuminuria: Effect of Antihypertensive Intervention. In: Mogensen, C.E. (eds) The Kidney and Hypertension in Diabetes Mellitus. Topics in Renal Medicine, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1974-1_20
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DOI: https://doi.org/10.1007/978-1-4757-1974-1_20
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-1976-5
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