Lecithin pp 37-45 | Cite as

Partial Synthesis of Glycerophospholipids

  • A. Hermetter
  • F. Paltauf
Part of the Advances in Behavioral Biology book series (ABBI, volume 33)


Glycerophospholipids obtained from natural sources, that is from plant, animal or microbial cells, are complex mixtures of phospholipid classes, subclasses and species. It is extremely difficult if not impossible to isolate, with available technology, individual phospholipid species from such mixtures. If one needs a chemically defined phospholipid, e.g., for biochemical or biophysical studies, for the preparation of lipid vesicles or liposomes, or as emulsifiers with well defined properties etc., then chemical synthesis is the only way to make these substances available. The use of synthetic methods is even more compulsory if the desired product is a radioactively or otherwise — spin, fluorescent or photoreactive — labeled phospholipid, or if it contains other “unnatural” rests, such as modified head groups or hydrophobic moieties.


Phosphatidic Acid Phospholipid Class Acyl Migration Amino Alcohol Partial Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • A. Hermetter
    • 1
  • F. Paltauf
    • 1
  1. 1.Institute of Biochemistry and Food ChemistryTechnical University of GrazAustria

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