Tubular Processing of Glomerular Ultrafiltrate: Mechanisms of Electrolyte and Water Transport

  • Esmail Koushanpour
  • Wilhelm Kriz


Once the glomerular filtrate is formed, the next major steps in the renal regulation of body fluids occur in the tubular exchanger. Here, as the filtrate flows under a hydrostatic pressure head along the various nephron segments, almost all the filtered water and solutes are reabsorbed from the tubules, while some organic compounds are secreted into the tubules, yielding a small, hypertonic volume of urine. The final volume and composition of this excreted urine will largely depend on the efficiency of these two tubular transport processes and their intrarenal and extrarenal regulation.


Proximal Tubule Distal Tubule Sodium Reabsorption Distal Convoluted Tubule Luminal Membrane 
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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Esmail Koushanpour
    • 1
  • Wilhelm Kriz
    • 2
  1. 1.Northwestern University Medical SchoolChicagoUSA
  2. 2.University of HeidelbergHeidelbergFederal Republic of Germany

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