Body Fluids: Normal Volumes and Compositions

  • Esmail Koushanpour
  • Wilhelm Kriz


We have just learned that the kidneys play a major role in stabilizing the volume and composition of body fluids. To proceed further, we must acquire a basic understanding of fluid and electrolyte balance, a subject that is of great clinical importance.


Test Substance Total Body Water Extracellular Volume Cartilage Volume Deuterium Oxide 
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  1. 1.
    Deane N: Methods of study of body water compartments, in Corcoran AC (ed): Methods in Medical Research. Chicago, Year Book Medical Publishers, Inc, 1952, vol 5.Google Scholar
  2. 2.
    Deane N, Smith HW: The distribution of sodium and potassium in man. J Clin Invest 1952; 31: 197–199.PubMedCrossRefGoogle Scholar
  3. 3.
    Edelman IS: Exchange of water between blood and tissues. Characteristics of deuterium oxide equilibration in body water. Am J Physiol 1952; 171: 279–296.PubMedGoogle Scholar
  4. 4.
    Edelman IS, James AH, Brooks L, et al: Body sodium and potassium. IV. The normal exchangeable sodium, its measurement and magnitude. Metabolism 1954; 3: 530–538.PubMedGoogle Scholar
  5. 5.
    Edelman IS, Leibman J: Anatomy of body water and electrolytes. Am J Med 1959; 27: 256–277.PubMedCrossRefGoogle Scholar
  6. 6.
    Frus-Hansen B: Changes in body water compartments during growth. Acta Paediatr 1957; 46 (suppl. 110): 1–68.CrossRefGoogle Scholar
  7. 7.
    Gamble JL: Chemical Anatomy, Physiology and Pathology of Extracellular Fluid. A Lecture Syllabus, ed 6. Cambridge, Mas, Harvard University Press, 1967.Google Scholar
  8. 8.
    Goldberger E: A Primer of Water, Electrolytes and Acid-Base Syndrome. Philadelphia, Lea and Febiger, 1975.Google Scholar
  9. 9.
    Greger R, Schlafler E, Lang F: Evidence for electroneutral sodium chloride cotransport in the cortical thick ascending limb of Henle’s loop of rabbit kidney. Pfluegers Arch 1983; 396: 308–314.CrossRefGoogle Scholar
  10. 10.
    Koushanpour E: Renal Physiology: Principles and Functions, ed 1. Philadelphia, WB Saunders Co, 1976.Google Scholar
  11. 11.
    Manery JF: Water and electrolyte metabolism. Physiol Rev 1954; 34: 334–417.PubMedGoogle Scholar
  12. 12.
    Pace N, Rathbun EN: Studies on body composition. HI. The body water and chemically combined nitrogen content in relation to fat content. J Biol Chem 1945; 158: 685–691.Google Scholar
  13. 13.
    Pitts RF: Physiology of the Kidney and Body Fluids, ed 3. Chicago, Year Book Medical Publishers, Inc, 1974.Google Scholar
  14. 14.
    Rathbun EN, Pace N: Studies on body composition. I. The determination of total body fat by means of the body specific gravity. J Biol Chem 1945; 158: 667–676.Google Scholar
  15. 15.
    Ruch TC, Patton HD: Physiology and Biophysics, ed 20. Philadelphia, WB Saunders Co, 1974.Google Scholar
  16. 16.
    Schultz S: Sodium-coupled solute transport by small intestine: A status report. Am J Physiol 1977; 233: E249 - E254.PubMedGoogle Scholar
  17. 17.
    Schultz AL, Hammarsten JF, Heller BI, et al: A critical comparison of the T-1824 dye and iodinated albumin methods for plasma volume measurement. J Clin Invest 1953; 32: 107–112.PubMedCrossRefGoogle Scholar
  18. 18.
    Skelton H: The storage of water by various tissues of extracellular fluid in man and dogs. J Clin Invest 1953;Google Scholar
  19. 19.
    Solomon AK: Equations for tracer experiments. J Clin Invest 1949; 28: 1297–1307.PubMedCrossRefGoogle Scholar
  20. 20.
    Walser M, Seldin DW, Grollman A: An evaluation of radiosulfate for the determination of the volume of the body. Arch Intern Med 1927; 40:140–52. 32: 299–311.Google Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Esmail Koushanpour
    • 1
  • Wilhelm Kriz
    • 2
  1. 1.Northwestern University Medical SchoolChicagoUSA
  2. 2.University of HeidelbergHeidelbergFederal Republic of Germany

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