HPLC-EC Determination of Physostigmine in Biological Samples

  • Robin Whelpton
  • Peter Hurst
Part of the Methodological Surveys in Biochemistry and Analysis book series (MSBA, volume 16 A)


An assay sensitive enough (<0.1 ng/ml) for pharmacokinetic studies after injected or oral doses of physostigmine in man. Fluids to be assayed: plasma, blood, urine.


Blood sampIes Tapered Tube Calabar Bean London Hospital Medical College Propyl Derivative 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Groff, W.A., Ellin, R.I. & Skalsky, P.L. (1977) J. Pharm. Sci.66, 389–391.CrossRefGoogle Scholar
  2. 2.
    Whelpton, R. (1983) J. Chromatog.272, 216–220.Google Scholar
  3. 3.
    Whelpton, R. & Moore, T. (1985) J. Chromatog.341, 361–371.Google Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • Robin Whelpton
    • 1
  • Peter Hurst
    • 1
  1. 1.Department of Pharmacology and TherapeuticsLondon Hospital Medical CollegeWhitechapel, LondonUK

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