The Wisconsin Epidemiologic Study of Diabetic Retinopathy a Comparison of Retinopathy in Younger and Older Onset Diabetic Persons
- 134 Downloads
In a population-based survey of diabetic persons, retinopathy was detected by stereoscopic color fundus photography in 70% of persons under 30 years of age at diagnosis and taking insulin (Group YO), in 62% of persons 30 years of age or older at diagnosis and taking insulin (Group 00-I) and in 36% of persons 30 years of age or older at diagnosis not taking insulin (Group 00-N). The mean duration of known diabetes was 14.6 years in Group YO, 11.0 years in Group 00-I and 6.9 years in Group 00-N. After 20 years of diabetes, proliferative retinopathy was present in about 50% of Group YO, about 25% of Group 00-I and about 5% of Group 00-N. After 15 years of diabetes, macular edema was present in about 18% of Group YO, about 20% of Group 00-I and about 12% of Group 00-N.
When present, macular edema tended to be associated with more hard exudate in Group 00-N.
KeywordsDiabetic Retinopathy Macular Edema Diabetic Macular Edema Proliferative Diabetic Retinopathy Early Treatment Diabetic Retinopathy Study
Unable to display preview. Download preview PDF.
- 1.L.M. Aiello, L.I. Rand, and J.C. Briones, Diabetic retinopathy in Joslin Clinic patients with adult-onset diabetes, Opthalmology, 88: 619–23 (1981).Google Scholar
- 2.D.J. Bartholomew, A test of homogeniety for ordered alternatives, Biometrika, 46: 328, p. 36–48 (1959).Google Scholar
- 3.F.L. Caird, A. Pirie, and T.G. Ramsell, Diabetes and the Eye, Blackwell Scientific Publications, Oxford, England, Chap. 6 (1969).Google Scholar
- 4.Diabetic Retinopathy Study Research Group, Report 7, A modification of the Airlie House classification of diabetic retinopathy, Invest. Ophthalmol. Vis. Sci. 21: 210–226 (1981).Google Scholar
- 5.Diabetic Retinopathy Study Research Group, Photocoagulation treatment of proliferative diabetic retinopathy: Clinical application of Diabetic Retinopathy Study (DRS) findings, DRS report number 8, Ophthalmology, 88: 583–600 (1981).Google Scholar
- 6.Early Treatment Diabetic Retinopathy Study Coordinating Center, Manual of Operations, Baltimore, Diabetic Retinopathy Coordinating Center, Chap. 11 (1980).Google Scholar
- 7.Early Treatment Diabetic Retinopathy Study Coordinating Center, Manual of Operations, Baltimore, Diabetic Retinopathy Coordinating Center, Chap. 5 and 18 (1980).Google Scholar
- 8.J. Harberg, D. Holladay, and S. Entine, WISAR: Wisconsin Storage and Retrieval System, Wisconsin Clinical Cancer Center, Madison, Wis., (1979).Google Scholar
- 12.R. Klein, B.E.K. Klein, and S.E. Moss, et al, The Wisconsin Epidemiologic Study of Diabetic Retinopathy, 4. Diabetic macular edema, Ophthalmology in press.Google Scholar
- 13.E.H. Kohner, The evolution and natural history of diabetic retinopathy, Int. Opthalmol. Clin. 18: 1–16 (1978).Google Scholar
- 14.P. Plamberg, M. Smith, and S. Waltman, et al., The natural history of retinopathy in insulin-dependent juvenile-onset diabetes, Ophthalmology, 88: 613–618 (1981).Google Scholar
- 16.Writing Committe on Behalf of the HDFP Cooperative Group, The Hypertension Detection and Follow-up Program, Prey. Med. 5: 207–315 (1976).Google Scholar